GLP-1(7-37)Acetate
- CAS No.
- 1450806-98-0
- Chemical Name:
- GLP-1(7-37)Acetate
- Synonyms
- GLP-1(7-37)Acetate;GLP-1(7-37) acetate(106612-94-6 free base);Inhibitor,inhibit,GCGR,Glucagon Receptor,GLP1(737) acetate(106612946 free base),GLP 1(7 37) acetate(106612 94 6 free base)
- CBNumber:
- CB1953736
- Molecular Formula:
- C153H232N40O49
- Molecular Weight:
- 3415.77
- MDL Number:
- MFCD16876067
- MOL File:
- 1450806-98-0.mol
GLP-1(7-37)Acetate price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-0089448 | GLP-1(7-37)acetate 98.65% | 1450806-98-0 | 1mg | $252 | 2021-12-16 | Buy |
ChemScene | CS-0089448 | GLP-1(7-37)acetate 98.65% | 1450806-98-0 | 5mg | $432 | 2021-12-16 | Buy |
ChemScene | CS-0089448 | GLP-1(7-37)acetate 98.65% | 1450806-98-0 | 10mg | $660 | 2021-12-16 | Buy |
ChemScene | CS-0089448 | GLP-1(7-37)acetate 98.65% | 1450806-98-0 | 25mg | $1080 | 2021-12-16 | Buy |
GLP-1(7-37)Acetate Chemical Properties,Uses,Production
Description
GLP-1(7-37) acetate is an intestinal insulinotropic hormone that augments glucose induced insulin secretion[1].
GLP-1(7-37) (0.5, 5 or 50 pmol/min/kg) infused during the second hour of a 2-hour 11-mM hyperglycemic clamp produces a dose-related enhancement of the glucose-stimulated increase in plasma insulin concentration and an increased rate of glucose infusion in rats[2].Infusion of GLP-1(7-37) (5 pmol/min/kg) from 1 hour through 7 hours produces a sustained increase in plasma insulin concentration relative to levels in rats infused with vehicle in rats with maintained glucose concentration at 11 mM[2]. Animal Model: Male Sprague-Dawley rats weighing 300 to 350 g with glucose IV at a variablerate for 7 hours to maintain plasma glucose concentration at 11 mM[2].
References
[1]. Sarrauste de Menthiere, C. et al. Structural requirements of the N-terminal region of GLP-1-[7-37]-NH2 for receptor interaction and cAMP production. European journal of medicinal chemistry 39, 473-480, doi:10.1016/j.ejmech.2004.02.002 (2004). [2]. Hargrove DM, et al. Glucose-dependent action of glucagon-like peptide-1 (7-37) in vivo during short- or long-term administration. Metabolism. 1995 Sep;44(9):1231-7.
GLP-1(7-37)Acetate Preparation Products And Raw materials
Raw materials
Preparation Products
GLP-1(7-37)Acetate Suppliers
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InvivoChem | 13549236410 | sales@invivochem.cn | China | 6712 | 58 |