ChemicalBook >> CAS DataBase List >>1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE

CAS No.
6001-64-5
Chemical Name:
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
Synonyms
MET;CHLOROBUTANOL HEMIHYDRATE;CHLORETONE;CHLOROBUTANOL HYDROUS;CHLORBUTE;CHLORBUTOL;MET HEMIHYDRATE;ACETONE CHLOROFORM;ACETONE CHLOROFORME;Proto-oncogene c-Met
CBNumber:
CB2134363
Molecular Formula:
C8H16Cl6O3
Molecular Weight:
372.93
MDL Number:
MFCD02179352
MOL File:
6001-64-5.mol
MSDS File:
SDS
Last updated:2023-09-07 14:58:50

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Properties

Melting point 77-79 °C(lit.)
Boiling point 173-175 °C
Flash point 100 °C
storage temp. 2-8°C
solubility Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent).
form Crystalline Powder, Crystals and/or Chunks
color White to almost white
Water Solubility Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water.
Merck 14,2129
BRN 878167
Stability Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents.
LogP 2.074 (est)
CAS DataBase Reference 6001-64-5
FDA UNII 3X4P6271OX

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26-36/37/39
WGK Germany  3
RTECS  UC0175000
TSCA  Yes
HS Code  29055900
NFPA 704
0
2 0

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SAB1305534 MONOCLONAL ANTI-BI-PHOSPHO-MET/HGFR(Y1234/Y1235) antibody produced in mouse clone 6AT1877, IgG fraction of antiserum, buffered aqueous solution 6001-64-5 400μl $481 2024-03-01 Buy
Sigma-Aldrich 112054 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate 98% 6001-64-5 50g $57 2024-03-01 Buy
Sigma-Aldrich 1112503 Chlorobutanol United States Pharmacopeia (USP) Reference Standard 6001-64-5 200mg $491 2024-03-01 Buy
Sigma-Aldrich Y0002029 Chlorobutanol hemihydrate European Pharmacopoeia (EP) Reference Standard 6001-64-5 Y0002029 $150 2023-01-07 Buy
Sigma-Aldrich 1.01005 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate EMPROVE? ESSENTIAL, Ph. Eur., BP, JP, NF 6001-64-5 1KG $221 2022-05-15 Buy
Product number Packaging Price Buy
SAB1305534 400μl $481 Buy
112054 50g $57 Buy
1112503 200mg $491 Buy
Y0002029 Y0002029 $150 Buy
1.01005 1KG $221 Buy

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Chemical Properties,Uses,Production

Chemical Properties

white crystalline solid

Uses

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate in combination with dimethyl sulfone, can serve as an appropriate solvent for the freeze drying of certain parenteral organic drugs, which have an increase in many factors such as stability, dissolution rate, dosing accuracy and sterility.

Uses

Pharmaceutic aid (antimicrobial agent).

Uses

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate converts benzisoxazole to α-aryloxyisobutyric acid. It forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.

brand name

Chloretone (Parke-Davis).

General Description

1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) converts benzisoxazole to α-aryloxyisobutyric acid. 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.

Biochem/physiol Actions

Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.

1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 257)Suppliers
Supplier Tel Email Country ProdList Advantage
Jiangxi Alpha Hi-tech Pharmaceutical Co., Ltd
510-85010237 overseamarketing@alphahi-tech.com CHINA 41 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58

View Lastest Price from 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE pictures 2023-09-07 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
6001-64-5
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
1,1,1-Trichloro-2-Methyl-2-Propanol Hemihydrate pictures 2023-09-06 1,1,1-Trichloro-2-Methyl-2-Propanol Hemihydrate
6001-64-5
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Guanlang Biotechnology Co., Ltd.
Chlorobutanol pictures 2023-05-11 Chlorobutanol
6001-64-5
US $50.00 / KG 1KG 99% 20MT JIANGXI ALPHA HI-TECH PHARMACEUTICAL CO., LTD
  • Chlorobutanol pictures
  • Chlorobutanol
    6001-64-5
  • US $50.00 / KG
  • 99%
  • JIANGXI ALPHA HI-TECH PHARMACEUTICAL CO., LTD
CHLOROBUTO HEMIHYDRATE CHLORETONE 0.5-WATER CHLORETONE HEMIHYDRATE CHLORBUTE CHLORBUTOL BETA,BETA,BETA-TRICHLORO-T-BUTANOL HEMIHYDRATE BETA,BETA,BETA-TRICHLORO-TERT-BUTYL ALCOHOL HEMIHYDRATE Acetonechloroform beta,beta,beta-Trichloro-tert-butyl Alcohol Chloretone Chlorbutanol HeMihydrate MONOCLONAL ANTI-BI-PHOSPHO-MET/HGFR(Y1234/Y1235) antibody produced in mouse Proto-oncogene c-Met Scatter factor receptor 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate 98% 1,1,1-Trichloro-2-methyl-propanol hydrat 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate β,β,β-Trichloro-tert-butyl alcohol hemihydrate Acetone chloroform ACETONE CHLOROFORM 'ACETONE CHLOROFORM' ACETONE CHLOROFORM 0.5-WATER ACETONE CHLOROFORM HEMIHYDRATE ACETONCHLOROFORM HEMIHYDRATE 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HYDRATE 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate,β,β,β-Trichloro-t-butanol, β,β,β-Trichloro-tert-butyl alcohol hemihydrate, Acetone chloroform, Chloretone, Chlorobutanol Chlorobutanol (200 mg) Chlorobutanol, Hydrous, NF 1,1,1-Trichloro-2-Methyl-2-propanol  1,1,1-Trichloro-2-Methyl-2-propanol heMihydrate, 98% 100GR 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL 0.5-WATER 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE 2,2,2-TRICHLORO-TERT BUTYL ALCOHOL TRICHLORO-TER BUTANOL HEMIHYDRATE TRICHLORO-TERT BUTANOL N-METHYL-N-ETHYLTRYPTAMINE > 100 Kghlorobutanol hemihydrate 2-Methyl-1,1,1-trichloro-2-propanol hemihydrate ACETONE CHLOROFORME β,β,β-Trichloro-tert-butyl alcohol hemihydrate CHLOROBUTANOL HEMIHYDRATE, PHARMA 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL 0.5H2O 2-Propanol, 1,1,1-trichloro-2-methyl-, hydrate (2:1) β,β,β-trichloro-t-butanol CHLORBUTOLHEMIHYDRATE CHLOROBUTANOL,HEMIHYDRATE,NF MET HEMIHYDRATE β,β,β-Trichloro-t-butanol, Acetone chloroform, Chloretone, Chlorobutanol, β,β,β-Trichloro-tert-butyl alcohol hemihydrate Acetone chloroform, Chlorobutanol, β,β,β-Trichloro-tert-butyl alcohol hemihydrate 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate,98% 1,1,1-trichloro-2-methyl-2-propanol hemihydrate 2( 1,1,1-Trichloro-2-methyl-2-propanol Hemihydrate> 6001-64-5 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Chlorobutanol? (pharmaceutical grade) SanlvShudingchunChlorobutanol Chlorobutanol (1112503) β,β,β-Trichloro-tert-butyl alcohol hemihydrate CHLOROBUTANOL HEMIHYDRATE CHLORETONE CHLOROBUTANOL HYDROUS MET 1,1,1-Trichloro-2-methylpropan-2-ol hydrate