CLOFOCTOL
- CAS No.
- 37693-01-9
- Chemical Name:
- CLOFOCTOL
- Synonyms
- Octofene;Gramplus;CLOFOCTOL;13C6]-Clofoctol;2-[2,4-DICHLOROBENZYL]-4-[1,1,3,3-TETRAMETHYLBUTYL]PHENOL;α-[2,4-Dichlorophenyl]-4-[1,1,3,3-tetramethylbutyl]-o-cresol;2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)phenol;2-((2,4-dichlorophenyl)methyl)-4-(1,1,3,3-tetramethylbutyl)-pheno;2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol;Phenol, 2-[(2,4-dichlorophenyl)methyl]-4-(1,1,3,3-tetramethylbutyl)-
- CBNumber:
- CB2197054
- Molecular Formula:
- C21H26Cl2O
- Molecular Weight:
- 365.34
- MDL Number:
- MFCD00079014
- MOL File:
- 37693-01-9.mol
- MSDS File:
- SDS
| Melting point | 78° |
|---|---|
| Boiling point | 447.7±40.0 °C(Predicted) |
| Density | 1.127±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO:100.0(Max Conc. mg/mL);273.72(Max Conc. mM) |
| pka | 10.09±0.45(Predicted) |
| FDA UNII | 704083NI0R |
| ATC code | J01XX03 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| WGK Germany | 2 |
| RTECS | SL0533000 |
| Toxicity | LD50 orally in male rats: >4 g/kg (Debat) |
CLOFOCTOL price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | C586943 | Clofoctol | 37693-01-9 | 1g | $40 | 2021-12-16 | Buy |
| TRC | C586943 | Clofoctol | 37693-01-9 | 2.5g | $85 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0016253 | CLOFOCTOL 95.00% | 37693-01-9 | 5MG | $501.18 | 2021-12-16 | Buy |
| ChemScene | CS-4755 | Clofoctol 99.93% | 37693-01-9 | 100mg | $60 | 2021-12-16 | Buy |
| Crysdot | CD31002050 | Clofoctol 98+% | 37693-01-9 | 100mg | $50 | 2021-12-16 | Buy |
CLOFOCTOL Chemical Properties,Uses,Production
Originator
Octofene,Debat,France,1978
Uses
antibacterial
Uses
Clofoctol is a bacteriostatic antibiotic used against gram-positive bacteria.
Definition
ChEBI: 2-[(2,4-dichlorophenyl)methyl]-4-(2,4,4-trimethylpentan-2-yl)phenol is a diarylmethane.
Manufacturing Process
The following were introduced into a 1 liter flask provided with a reflux
condenser: 206 g (1 mol) of p-(1,1,3,3-tetramethylbutyl)-phenol, 147 g (0.75
mol) of 2,4-dichlorobenzyl chloride, 27 g (0.2 mol) of pure melted zinc
chloride, and 750 ml of anhydrous chloroform.
The mixture was heated to reflux for 24 hours. The chloroformic reaction
mixture was washed with water, and then dried over anhydrous sodium
sulfate. The chloroform was evaporated off and the oil obtained was
fractionally distilled under a pressure of 0.2 mm Hg. The fraction distilling at
140°C to 160°C, being the desired product indicated above, was collected and
crystallized. Yield: 94 g (32% of theory); MP 78°C (after recrystallization in
petroleum ether).
Therapeutic Function
Antiinfective, Bacteriostatic
CLOFOCTOL Preparation Products And Raw materials
Raw materials
Preparation Products
CLOFOCTOL Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33349 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3868 | 58 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2985 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |