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ChemicalBook >> CAS DataBase List >> (R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole

(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole

(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Structure
(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole structure
CAS No.
180637-88-1
Chemical Name:
(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole
Synonyms
interMediates of eletriptan hydrobroMide;(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole;Ethanone, 1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indol-1-yl]-
CBNumber:
CB22671455
Molecular Formula:
C24H26N2O3S
Molecular Weight:
422.54
MDL Number:
MOL File:
180637-88-1.mol
MSDS File:
SDS
Last updated:2023-11-15 11:56:25
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(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Properties

Boiling point 620.7±55.0 °C(Predicted)
Density 1.23±0.1 g/cm3(Predicted)
pka 10.23±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS05
Signal word  Danger
Hazard statements  H317-H318
Precautionary statements  P280-P305+P351+P338-P310-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501

(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Chemical Properties,Uses,Production

Definition

(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole is an intermediate of Eletriptan hydrobromide which is used to relieve pain or symptoms associated with migraine headaches.

(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole synthesis

5535-48-8
143322-57-0
180637-88-1
Synthesis of (R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole from Phenyl vinyl sulfone and (R)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole

(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Preparation Products And Raw materials

Raw materials

Preparation Products

Eletriptan hydrobromide

(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Qiwei Pharmatech Co.,Ltd
13282840061 mw@qwpharmatech.com China 109 58
Unibest Industrial Co.,Ltd. 		+86-8657427855777 +86-18758850676 info@unibestcn.com China 348 58
Henan Aochuang Chemical Co.,Ltd. 		+86-0371-63689365 +8618638391208 sales@aochuangchem.com China 9425 58
Zhengzhou Acme Chemical Co., Ltd. 0371-0371-63315541 13323832564 3001332135@qq.com China 8922 58
Suzhou Meishi Biotechnology Co., Ltd. 1173954148q meishipharma@126.com China 20035 58
Baoji Didu Pharmaceutical and Chemical Co., Ltd 029-61856358 15829046862 1035@dideu.com China 10011 58
Supplier Advantage
Hangzhou Qiwei Pharmatech Co.,Ltd
58
Unibest Industrial Co.,Ltd. 		58
Henan Aochuang Chemical Co.,Ltd. 		58
Zhengzhou Acme Chemical Co., Ltd. 58
Suzhou Meishi Biotechnology Co., Ltd. 58
Baoji Didu Pharmaceutical and Chemical Co., Ltd 58
(R)-1-acetyl-5-[2-(phenylsulfonyl)ethyenyl]-3-(N-methylpyrrolidin-2-ylmethyl)-1H-indole interMediates of eletriptan hydrobroMide Ethanone, 1-[3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-5-[2-(phenylsulfonyl)ethenyl]-1H-indol-1-yl]- 180637-88-1