ChemicalBook >> CAS DataBase List >>1,8-Naphthyridine

1,8-Naphthyridine

CAS No.
254-60-4
Chemical Name:
1,8-Naphthyridine
Synonyms
1, 8 - nalidixic;1,8-NAPHTHYRIDINE;1,8-Pyridopyridine;1,8-Diazanapthalene;1,8-Naphthyridine>1,8-DIAZANAPHTHALENE;PYRIDO[2,3-B]PYRIDINE;1,8-NAPHTHYRIDINE 98+%;1,8-Diazanaphthalene 98%;1,8-Naphthyridine(6CI,7CI,8CI,9CI)
CBNumber:
CB2352000
Molecular Formula:
C8H6N2
Molecular Weight:
130.15
MDL Number:
MFCD00059751
MOL File:
254-60-4.mol
MSDS File:
SDS
Last updated:2023-06-08 17:06:37

1,8-Naphthyridine Properties

Melting point 99.8-99.9°C
Boiling point 248.9±13.0 °C(Predicted)
Density 1.183±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka 3.39
form powder to crystal
pka 3.55±0.10(Predicted)
color White to Light yellow to Light orange
InChIKey FLBAYUMRQUHISI-UHFFFAOYSA-N
CAS DataBase Reference 254-60-4(CAS DataBase Reference)
FDA UNII 043R04VL4M

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
HazardClass  IRRITANT
HS Code  2902900000
NFPA 704
0
1 0

1,8-Naphthyridine price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical N0464 1,8-Naphthyridine >98.0%(GC) 254-60-4 1g $146 2024-03-01 Buy
TCI Chemical N0464 1,8-Naphthyridine >98.0%(GC) 254-60-4 100mg $25 2024-03-01 Buy
TRC B504303 1,8-Naphthyridine 254-60-4 50mg $60 2021-12-16 Buy
Matrix Scientific 018153 [1,8]Naphthyridine 254-60-4 500mg $52 2021-12-16 Buy
SynQuest Laboratories 3H32-1-DP 1,8-Diazanaphthalene 254-60-4 1g $150 2021-12-16 Buy
Product number Packaging Price Buy
N0464 1g $146 Buy
N0464 100mg $25 Buy
B504303 50mg $60 Buy
018153 500mg $52 Buy
3H32-1-DP 1g $150 Buy

1,8-Naphthyridine Chemical Properties,Uses,Production

Description

1,8-Naphthyridine is an organic compound with the formula C8H6N2. It is the most well-studied of the six isomeric naphthyridines, a subset of diazanaphthalenes with nitrogen in the separate rings. Enoxacin, nalidixic acid, and trovafloxacin are 1,8-naphthyridine derivatives with antibacterial properties related to the fluoroquinolones.

Uses

1,8-naphthyridine (napy) and its simplest 2-methyl and 2,7-dimethyl derivatives may act as monodentate and bidentate ligands, resembling the behavior of the carboxylate ligands.

Definition

ChEBI: 1,8-naphthyridine is a naphthyridine in which the nitrogens are situated at positions 1 and 8.

Purification Methods

Purify 1,8-naphthyridine through an Al2O3 column and elute with toluene and pet ether, evaporate the eluate, crystallise the residue from pet ether (b 60-80o), and sublime it at 80o/13mm. The picrate [15936-16-0] has m 207-208o (from EtOH), and the methiodide has m 180-181o (from EtOH). [Hawes & Wibberley J Chem Soc (C) 1564 1967, UV: Armarego Physical Methods in Heterocyclic Chemistry (Ed Katritzky, Academic Press) Vol III 134 1971, Beilstein 23 II 178, 23 III/IV 1237.]

1,8-Naphthyridine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 142)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
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Alchem Pharmtech,Inc.
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SIMAGCHEM CORP
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Shanghai UCHEM Inc.
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View Lastest Price from 1,8-Naphthyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,8-NAPHTHYRIDINE  pictures 2021-10-27 1,8-NAPHTHYRIDINE
254-60-4
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
1,8-NAPHTHYRIDINE pictures 2020-01-15 1,8-NAPHTHYRIDINE
254-60-4
US $1.00 / g 1g 99% 1000KGS Career Henan Chemical Co
1,8-DIAZANAPHTHALENE 1,8-NAPHTHYRIDINE PYRIDO[2,3-B]PYRIDINE 1,8-Pyridopyridine 1,8-Naphthyridine(6CI,7CI,8CI,9CI) 1,8-NAPHTHYRIDINE 98+% 1,8-Diazanapthalene 1,8-Diazanaphthalene Pyrido[2,3-b]pyridine 1,8-Diazanaphthalene 98% 1,8-Naphthyridine> 1, 8 - nalidixic 1,8-NAPHTHYRIDINE ISO 9001:2015 REACH 1,8-Naphthyridine (6CI, 7CI, 8CI, 9CI, ACI) 254-60-4 PYRIDINE