CHOLANIC ACID

CAS No.
25312-65-6
Chemical Name:
CHOLANIC ACID
Synonyms
CHOLANIC ACID;Einecs 246-816-2
CBNumber:
CB2365660
Molecular Formula:
C24H40O2
Molecular Weight:
360.57
MDL Number:
MFCD00021166
MOL File:
25312-65-6.mol
Last updated:2023-07-18 08:29:08

CHOLANIC ACID Properties

Melting point 163-164°; mp 163.5°
alpha D20 +21.7° (chloroform)
Boiling point 432.57°C (rough estimate)
Density 1.0086 (rough estimate)
refractive index 1.4480 (estimate)
pka 4.76±0.10(Predicted)
FDA UNII NS0L7RS7DA

CHOLANIC ACID Chemical Properties,Uses,Production

Definition

ChEBI: A steroid acid that consists of cholane having a carboxy group in place of the methyl group at position 24.

Purification Methods

Crystallise 5-cholanic acid from EtOH, Me2CO or AcOH. The ethyl ester has m 93-94o (from 80% EtOH), b 273o/12mm, [] D 20 +21o (CHCl3), and the methyl ester has m 86-87o (from MeOH) after purification through Al2O3 and eluting with *C6H6, and [] D 20 +21.2o (CHCl3). The 1H NMR (CDCl3) for the C18 & C19 protons has at 0.65 and 0.92ppm [see 5-cholanic acid above, Mandava et al. Steroids 23 357 1974]. [Stoll et al. Helv Chim Acta 18 644 1935, Huang-Minlon J Am Chem Soc 7 1 330 1949, Beilstein 9 III 2656, 9 IV 1992.]

2204-14-0
25312-65-6
Synthesis of CHOLANIC ACID from Cholan-24-oic acid, methyl ester, (5β)-

CHOLANIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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Einecs 246-816-2 CHOLANIC ACID 25312-65-6