ChemicalBook >> CAS DataBase List >>4-Hydroxyquinoline

4-Hydroxyquinoline

CAS No.
611-36-9
Chemical Name:
4-Hydroxyquinoline
Synonyms
KYNURINE;AKOS 222-32;4-QUINOLINOL;QUINOLIN-4-OL;4-HydroxyquinoL;4-Quinolinol 98%;4-Quinolinol >1H-Quinolin-4-one;4(1H)-QUINOLINONE;4-hydroxy-quinolin
CBNumber:
CB2372460
Molecular Formula:
C9H7NO
Molecular Weight:
145.16
MDL Number:
MFCD00006777
MOL File:
611-36-9.mol
MSDS File:
SDS
Last updated:2024-01-16 16:12:45

4-Hydroxyquinoline Properties

Melting point 200-202 °C(lit.)
Boiling point 264.27°C (rough estimate)
Density 1.1555 (rough estimate)
refractive index 1.4500 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in methanol.
form Crystalline Powder or Needles
pka 2.23, 11.28(at 20℃)
color Light beige to yellow
Water Solubility 4.8g/L(15 ºC)
BRN 1524969
InChIKey PMZDQRJGMBOQBF-UHFFFAOYSA-N
LogP 2.450 (est)
CAS DataBase Reference 611-36-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII M1O131WXFO
NIST Chemistry Reference 4-Quinolinol(611-36-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  VC4070000
HS Code  29334900
NFPA 704
0
2 0

4-Hydroxyquinoline price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich H58005 4-Quinolinol 98% 611-36-9 1g $25.9 2024-03-01 Buy
Sigma-Aldrich H58005 4-Quinolinol 98% 611-36-9 5g $47.6 2024-03-01 Buy
TCI Chemical Q0029 4-Quinolinol >98.0%(GC)(T) 611-36-9 5g $70 2024-03-01 Buy
TCI Chemical Q0029 4-Quinolinol >98.0%(GC)(T) 611-36-9 25g $277 2024-03-01 Buy
Alfa Aesar A15859 4-Hydroxyquinoline, 98% 611-36-9 1g $43.65 2024-03-01 Buy
Product number Packaging Price Buy
H58005 1g $25.9 Buy
H58005 5g $47.6 Buy
Q0029 5g $70 Buy
Q0029 25g $277 Buy
A15859 1g $43.65 Buy

4-Hydroxyquinoline Chemical Properties,Uses,Production

Description

4-Hydroxyquinoline is a quinoline alkaloid that has been found in Z. lotus honeys. It is a core component of alkyl-4-hydroxyquinoline quorum sensing molecules such as 2-heptyl-3-hydroxy-4(1H)-quinolone and 2-nonyl-3-hydroxy-4-quinolone. 4-Hydroxyquinoline has been used as a precursor in the synthesis of compounds with antibacterial activity. It has also been used as a fluorescent detection reagent for iron(III) in bovine liver samples.

Chemical Properties

LIGHT BEIGE TO YELLOWISH CRYST. POWDER OR NEEDLES

Uses

4-Hydroxyquinoline is a medical raw material.

Uses

4-Hydroxyquinolineis a hydroxylated quinoline derivative with antimicrobial activity. 4-Hydroxyquinoline showed growth-inhibitory effects against intestinal bacteria. 4-Hydroxyquinoline act as sacrifi cial scavengers of the photogenerated oxygen species and has been shown to prevent the photodegradation of riboflavin.

Definition

ChEBI: A monohydroxyquinoline carrying a hydroxy group at position 4.

Synthesis Reference(s)

Journal of the American Chemical Society, 68, p. 1264, 1946 DOI: 10.1021/ja01211a038

General Description

4-Quinolinol (4-quinolone) is a quinolone compound which forms the core moiety of antibacterials such as norfloxacin, nalidixic acid, ciprofloxacin and cinoxacin.

Biological Activity

4-hydroxyquinoline is a hydroxylated quinoline derivative with antimicrobial activity. it shows growth-inhibitory effects against intestinal bacteria. it also can be used as sacrificial scavengers of the photogenerated oxygen species.

62-53-3
611-36-9
Synthesis of 4-Hydroxyquinoline from Aniline
Global( 454)Suppliers
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View Lastest Price from 4-Hydroxyquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
B-[4-(trans-4-Ethylcyclohexyl)-2-fluorophenyl]boronic acid pictures 2024-01-14 B-[4-(trans-4-Ethylcyclohexyl)-2-fluorophenyl]boronic acid
611-36-9
US $8.00-0.60 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-Hydroxyquinoline pictures 2023-07-26 4-Hydroxyquinoline
611-36-9
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
4-Hydroxyquinoline pictures 2023-06-17 4-Hydroxyquinoline
611-36-9
US $9.00 / KG 1KG 99.9 1 ton Hebei Guanlang Biotechnology Co,.LTD
QUINOLIN-4-OL QUINOLIN-4(1H)-ONE KYNURINE 4-hydroxy-quinolin 1H-Quinolin-4-one Quinoline, 4-hydroxy- 4-Hydroxyquinoline98% 4-Quinolinol,4-Hydroxyquinoline 4-Hydroxyquinoline, 98% 10GR 4-hydroxyquatolate 4-Quinolinol 98% 4(1H)-QUINOLINONE 4-QUINOLINOL 4-HYDROXYQUINOLINE 4-HYDROXY-1-AZANAPHTHALENE HYDROXYQUINOLINE,4- 4-Hydroxyquinoline, >=98.5% AKOS 222-32 4-Quinolinol > 4-HydroxyquinoL 4-Hydroxyquinoline ISO 9001:2015 REACH Bedaquiline Impurity 15 611-36-9 C9H8NO ALCOHOL Hydroxyquinolines Quinolines Building Blocks Heterocyclic Building Blocks Building Blocks C8 to C10 Chemical Synthesis Heterocyclic Building Blocks Quinoline&Isoquinoline Quinolines Hydroxyquinolines quinoline Quinolines, Quinazolines and derivatives Heterocyclic Series Alcohols and Derivatives Heterocycles