ChemicalBook >> CAS DataBase List >>(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid structure

CAS No.: 189684-50-2

Chemical Name:: (4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Synonyms: N-ACETYL-ASP-GLU-VAL-ASP-PNA;N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-α-asparagine;L-α-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-;N-Acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-N-(4-nitrophenyl)-L-alpha-asparagine;(4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxymethyl)-10-isopropyl-13-((4-nitrophenyl)carbamoyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid;(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

CBNumber:: CB23938085

Molecular Formula:: C26H34N6O13

Molecular Weight:: 638.59

MDL Number:

MOL File:: 189684-50-2.mol

Last updated:2023-05-21 10:59:17

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(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid Properties

Boiling point	1187.0±65.0 °C(Predicted)
Density	1.448±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	Acetonitrile:Methanol (1:1): 1 mg/ml
form	A crystalline solid
pka	4.03±0.10(Predicted)

(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid price More Price(7)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	14460	Ac-DEVD-pNA	189684-50-2	5mg	$86	2024-03-01	Buy
Cayman Chemical	14460	Ac-DEVD-pNA	189684-50-2	10mg	$153	2024-03-01	Buy
Cayman Chemical	14460	Ac-DEVD-pNA	189684-50-2	1mg	$32	2024-03-01	Buy
BroadPharm	BP-23537	Ac-DEVD-pNA 95%	189684-50-2	10mg	$200	2021-12-16	Buy
DC Chemicals	DC11458	Ac-DEVD-pNA(Caspase-3Substrate) >98%	189684-50-2	100mg	$750	2021-12-16	Buy

Product number	Packaging	Price	Buy
14460	5mg	$86	Buy
14460	10mg	$153	Buy
14460	1mg	$32	Buy
BP-23537	10mg	$200	Buy
DC11458	100mg	$750	Buy

(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid Chemical Properties,Uses,Production

Description

During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-pNA is a para-nitro aniline chromophore cleaved by caspases (K_m = 18, 11, 32, 180, and 12 μM for caspases-1, -3, -4, -6, and -7, respectively). It is not cleaved by caspase-2. Cleavage is monitored colorimetrically at 405 nm.

(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid Suppliers

Global( 14)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Aromsyn Co., Ltd.	+86-0571-85585865 +8613336024896	CB@aromsyn.com	China	19185	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9756	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
Hangzhou Go Top Peptide Biotech	0571-88211921 13355716090	Sales@gotopbio.com	China	2831	58
TCI (Shanghai) Chemical Trading Co., Ltd.	021-61109150	sales@tcisct.com	China	31163	58
Shaoxing Junyu Biotechnology Co., LTD	0571-88211921 15572296305	sales4@gotopbio.com	China	5144	58
Hangzhou Baige Pharmaceutical Technology Co. , Ltd.	0571-85350119 15888826472	15888826472@163.com	China	2729	58
Combio (Suzhou) Ltd.	0512-51886999 17706251929	office@combiosz.com	China	2224	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58

Supplier	Advantage
Shenzhen Nexconn Pharmatechs Ltd	58
Aromsyn Co., Ltd.	58
Shanghai Chaolan Chemical Technology Center	58
DC Chemicals	58
Hangzhou Go Top Peptide Biotech	58
TCI (Shanghai) Chemical Trading Co., Ltd.	58
Shaoxing Junyu Biotechnology Co., LTD	58
Hangzhou Baige Pharmaceutical Technology Co. , Ltd.	58
Combio (Suzhou) Ltd.	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

(4S)-4-[[(2S)-2-acetamido-3-carboxypropanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-(4-nitroanilino)-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid N-ACETYL-ASP-GLU-VAL-ASP-PNA L-α-Asparagine, N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)- N-Acetyl-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-N-(4-nitrophenyl)-L-alpha-asparagine N-acetyl-L-α-aspartyl-L-α-glutamyl-L-valyl-N-(4-nitrophenyl)-L-α-asparagine (4S,7S,10S,13S)-7-(2-carboxyethyl)-4-(carboxymethyl)-10-isopropyl-13-((4-nitrophenyl)carbamoyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid 189684-50-2