ChemicalBook >> CAS DataBase List >>HARRINGTONINE
HARRINGTONINE
- CAS No.
- 26833-85-2
- Chemical Name:
- HARRINGTONINE
- Synonyms
- HT;nsc124147;(3(r))-ter;HARRINGTONIN;HARRINGTONINE;2'R-HARRINGTONINE;HARRINGTONINE98%,99%;Harringtonine 26833-85-2;alkaloidcfromcephalotaxus;HARRINGTONINE(P) USP/EP/BP
- CBNumber:
- CB2702955
- Molecular Formula:
- C28H37NO9
- Molecular Weight:
- 531.6
- MDL Number:
- MFCD28978177
- MOL File:
- 26833-85-2.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:02:15
| Melting point | 73～75℃ |
|---|---|
| Boiling point | 679.4±55.0 °C(Predicted) |
| Density | 1.35±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMF: 25 mg/ml; DMSO: 25 mg/ml; Ethanol: 25 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
| form | A crystalline solid |
| pka | 11.62±0.29(Predicted) |
| FDA UNII | 088662H40F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H310-H300-H330 | |||||||||
| Precautionary statements | P262-P264-P270-P280-P302+P350-P310-P322-P361-P363-P405-P501-P264-P270-P301+P310-P321-P330-P405-P501-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501 | |||||||||
| RIDADR | 1544 | |||||||||
| HazardClass | 6.1(a) | |||||||||
| PackingGroup | II | |||||||||
| NFPA 704 |
|
HARRINGTONINE price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 15361 | Harringtonine ≥95% | 26833-85-2 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 15361 | Harringtonine ≥95% | 26833-85-2 | 5mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 15361 | Harringtonine ≥95% | 26833-85-2 | 10mg | $172 | 2024-03-01 | Buy |
| Usbiological | 300401 | Harringtonine | 26833-85-2 | 20mg | $335 | 2021-12-16 | Buy |
| TRC | H105285 | Harringtonin | 26833-85-2 | 10mg | $150 | 2021-12-16 | Buy |
HARRINGTONINE Chemical Properties,Uses,Production
Description
The full structure of harringtonine has now been established from a study of the hydrolysis products of this base.
Description
Harringtonine is a natural alkaloid that inhibits protein synthesis at low micromolar concentrations. It immobilizes ribosomes immediately after the initiation of translation. While harringtonine has drawn some interest in mitigating cancer, its homolog homoharrington is more effective, particularly for chronic myelogenous leukemia. The ability of harringtonine to immobilize initiating ribosomes can be used to capture ribosome-
Chemical Properties
White Solid
Uses
A natural product with significant antitumor activities.
Uses
specific anti-leukemia drug
Definition
ChEBI: Harringtonine is an alkaloid.
References
Mikolajczak, Powell, Smith, Tetrahedron, 28, 1995 (1972)
Kelly, McKenna, Christenson, Tetrahedron Lett., 35m (1973)
HARRINGTONINE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 158)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569266 15319487004 | 1015@dideu.com | China | 2263 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 | marketing1@neostarunited.com | China | 8349 | 58 |
View Lastest Price from HARRINGTONINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-28 | HARRINGTONINE
26833-85-2
|
US $0.00-0.00 / mg | 20mg | 98% HPLC | 100kg | Changsha Staherb Natural Ingredients Co., Ltd. | |
 |
2023-02-24 | Harringtonine
26833-85-2
|
US $0.00 / mg | 5mg | ≥95%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2022-05-14 | HARRINGTONINE
26833-85-2
|
US $1.10 / g | 1g | 99.9% Min | 100 Tons | Dideu Industries Group Limited |
-
- HARRINGTONINE
26833-85-2
- US $0.00-0.00 / mg
- 98% HPLC
- Changsha Staherb Natural Ingredients Co., Ltd.
-
- Harringtonine
26833-85-2
- US $0.00 / mg
- ≥95%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- HARRINGTONINE
26833-85-2
- US $1.10 / g
- 99.9% Min
- Dideu Industries Group Limited
(3(r))-ter
4-methyl-cephalotaxin2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate(es
alkaloidcfromcephalotaxus
cephalotaxine,4-methyl(2r)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioat
nsc124147
HARRINGTONIN
HARRINGTONINE
HT
2'R-HARRINGTONINE
Cephalotaxine, 4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate (ester)
HARRINGTONINE98%,99%
2’R-Harringtonine,Harringtonin
3-[4-Methyl (2R)-2-hydroxy-2-(3-hydroxy-3-Methylbutyl)butanedioate]cephalotaxine
3-methylbutyl)butanedioate (ester), [3(R)]-
Cephalotaxine, 4-methyl 2-hydroxy-2-(3-hydroxy-
2-Hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioic acid 1-[(3R)-3-deoxycephalotaxin-3-yl]4-methyl ester
Harringtonine, 98%, from Taxus chinensis (Pilg.) Rehder
Harringtonine 26833-85-2
Cephalotaxine, 3-[4-methyl (2R)-2-hydroxy-2-(3-hydroxy-3-methylbutyl)butanedioate]
HARRINGTONINE(P) USP/EP/BP
26833-85-2
C28H37NO9
Intermediates & Fine Chemicals
Pharmaceuticals
Alkaloids