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METHAQUALONE HYDROCHLORIDE

METHAQUALONE HYDROCHLORIDE structure

CAS No.: 340-56-7

Chemical Name:: METHAQUALONE HYDROCHLORIDE

Synonyms: melsedin;Einecs 206-431-2;mtqhydrochloride;Methaqualone HCl;Revonal hydrochloride;METHAQUALONE HYDROCHLORIDE;KJUHIXIWKSVBKB-UHFFFAOYSA-N;methylquinazolonehydrochloride;2-methyl-3-tolylchinazolon-4hydrochloride;2-metil-3-(o-tolil)-4-chinazolonechloridrato

CBNumber:: CB2765318

Molecular Formula:: C16H15ClN2O

Molecular Weight:: 286.76

MDL Number:: MFCD00058185

MOL File:: 340-56-7.mol

Last updated:2023-05-04 15:14:09

METHAQUALONE HYDROCHLORIDE Properties

Melting point	255-265°
Flash point	11 °C
storage temp.	2-8°C
EWG's Food Scores	1
FDA UNII	RJQ4G25ZRH

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P264-P270-P301+P310-P321-P330-P405-P501
Hazard Codes	Xn,T,F
Risk Statements	22-39/23/24/25-23/24/25-11
Safety Statements	7-16-36/37-45
RIDADR	UN 2811 6.1/PG 3
WGK Germany	3
RTECS	VA4025000
HazardClass	6.1(b)
PackingGroup	III

METHAQUALONE HYDROCHLORIDE Chemical Properties,Uses,Production

Originator

Quaalude ,Lemmon,US,1965

Manufacturing Process

Anthranilic acid (1 part) is dissolved in acetic anhydride (2 parts) and the temperature raised progressively to 190° to 200°C while distillation takes place. The last traces of acetic acid are removed under vacuum and, after cooling to about 50° to 60°C, o-toluidine (1 part) is added in portions.
The temperature is then raised to 170° to 200°C when the excess water and o-toluidine is gradually distilled off, finally maintaining the temperature at 180° to 200°C for 2 hours. After cooling to about 100°C dilute hydrochloric acid (3 parts) is added and the mixture boiled and stirred. The solution is then neutralized with NaOH with stirring and the product which separates is recrystallized twice from alcohol after decolorizing with carbon. Yield: 70% of theoretical, LIP 114° to 115°C.

Therapeutic Function

Hypnotic

Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. An experimental teratogen. Experimental reproductive effects. Human systemic effects. convulsions, dyspnea, pulse rate increase. When heated to decomposition it emits very toxic fumes of NOx and HCl.

METHAQUALONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Acetic anhydride Anthranilic acid Hydrochloric acid o-Toluidine

Preparation Products

340-56-7(METHAQUALONE HYDROCHLORIDE)Related Search:

METHAQUALONE HYDROCHLORIDE METHAQUALONE 6,8-DICHLORO-2-(CHLOROMETHYL)-3-(2,6-DIMETHYLPHENYL)-4(3H)-QUINAZOLINONE 2-[(BUTYLSULFANYL)METHYL]-6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-4(3H)-QUINAZOLINONE 6-CHLORO-2-([(4-CHLOROPHENYL)SULFANYL]METHYL)-3-(2-METHYLPHENYL)-4(3H)-QUINAZOLINONE

6-CHLORO-2-([(4-METHOXYPHENYL)SULFANYL]METHYL)-3-(2-METHYLPHENYL)-4(3H)-QUINAZOLINONE 3-(4-CHLORO-2-METHYLPHENYL)-2-([(2-METHOXYPHENYL)SULFANYL]METHYL)-4(3H)-QUINAZOLINONE 6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-2-([(4-FLUOROPHENYL)SULFANYL]METHYL)-4(3H)-QUINAZOLINONE 2-(CHLOROMETHYL)-3-(4-CHLORO-2-METHYLPHENYL)-4(3H)-QUINAZOLINONE 2-[(BENZYLSULFANYL)METHYL]-6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-4(3H)-QUINAZOLINONE

6-CHLORO-2-([(3-CHLOROPHENYL)SULFANYL]METHYL)-3-(2-METHYLPHENYL)-4(3H)-QUINAZOLINONE 6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-2-([(4-METHOXYPHENYL)SULFANYL]METHYL)-4(3H)-QUINAZOLINONE 3-(4-CHLORO-2-METHYLPHENYL)-2-([(2,6-DICHLOROPHENYL)SULFANYL]METHYL)-4(3H)-QUINAZOLINONE 6-CHLORO-2-([(2,6-DICHLOROPHENYL)SULFANYL]METHYL)-3-(2-METHYLPHENYL)-4(3H)-QUINAZOLINONE 6-CHLORO-3-(2-METHYLPHENYL)-2-(([3-(TRIFLUOROMETHYL)PHENYL]SULFANYL)METHYL)-4(3H)-QUINAZOLINONE

2-([(4-BROMOPHENYL)SULFANYL]METHYL)-6-CHLORO-3-(2-METHYLPHENYL)-4(3H)-QUINAZOLINONE 2-([(4-BROMOPHENYL)SULFANYL]METHYL)-6,8-DICHLORO-3-(2,6-DIMETHYLPHENYL)-4(3H)-QUINAZOLINONE 2-Metil-3-(2-carbossietildietilammino-6-metil-fenil)-4-chinazolone clo ridrate [Italian]

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mtqhydrochloride 2-METHYL-3-[2-METHYLPHENYL]-4[3H]-QUINAZOLINONE HYDROCHLORIDE METHAQUALONE HYDROCHLORIDE METHAQUALONE HYDROCHLORIDE--DEA*SCHEDULE I ITEM 4(3H)-Quinazolinone, 2-methyl-3-(2-methylphenyl)-, monohydrochloride Revonal hydrochloride 2-Methyl-3-tolylchinazolon-4 hydrochloride [german] 2-Metil-3-(o-tolil)-4-chinazolone chloridrato [italian] 4(3H)-Quinazolinone, 2-methyl-3-o-tolyl-, hydrochloride 4(3H)-Quinazolinone, 2-methyl-3-o-tolyl-, monohydrochloride (8ci) Einecs 206-431-2 Methaqualone HCl 2-methyl-3-(o-tolyl)-4-quinazolonehydrochloride 2-methyl-3-o-tolyl-4(3h)-quinazolinonehydrochloride 2-methyl-3-o-tolyl-4(3h)-quinazolinonhydrochloride 2-methyl-3-tolylchinazolon-4hydrochloride 2-metil-3-(o-tolil)-4-chinazolonechloridrato melsedin methylquinazolonehydrochloride KJUHIXIWKSVBKB-UHFFFAOYSA-N 340-56-7 C16H14N2OHCl Analytical Chromatography Product Catalog Analytical Standards Alphabetic META - METH