COMPLEMENT C2-DEPLETED SERUM, HUMAN

CAS No.
80295-40-5
Chemical Name:
COMPLEMENT C2-DEPLETED SERUM, HUMAN
Synonyms
C2-DEPLETED SERUM, HUMAN;complement C2 deficient serum;COMPLEMENT C2-DEPLETED SERUM, HUMAN;COMPLEMENT C2 DEFICIENT SERUM HUMAN
CBNumber:
CB3158632
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00130835
MOL File:
Mol file

COMPLEMENT C2-DEPLETED SERUM, HUMAN Properties

storage temp. -70°C

SAFETY

Risk and Safety Statements

Hazard Codes  B
WGK Germany  3

COMPLEMENT C2-DEPLETED SERUM, HUMAN price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C0913 Complement C2 deficient serum human for complement assays 80295-40-5 1ml $309 2024-03-01 Buy
Product number Packaging Price Buy
C0913 1ml $309 Buy

COMPLEMENT C2-DEPLETED SERUM, HUMAN Chemical Properties,Uses,Production

Uses

C2 is a critical protease for compliment activation, which supports bacterial killing via phagocytes. C2 can be used in research to explore the mechanisms by which bacterial pathogens evade detection by the compliment system. One such mechanism by the bacteria Pseudomonas aeruginosa, uses the alkaline protease (AprA) to degrade and cleave C2 which ultimately interferes with the classical and lectin pathways. Research has shown that C2 deficiency results in an increased risk of infection by Streptococcus pyogenes through impaired phaogocytosis and neutrophil dependent killing.

Biochem/physiol Actions

Heritable complement C2 deficiency can manifest as a number of severe dermatological disorders, including discoid lupus erythematosus, idiopathic atrophoderma, and dermatomyositis.

COMPLEMENT C2-DEPLETED SERUM, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

COMPLEMENT C2-DEPLETED SERUM, HUMAN Suppliers

Global( 6)Suppliers
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Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Supplier Advantage
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C2-DEPLETED SERUM, HUMAN COMPLEMENT C2 DEFICIENT SERUM HUMAN COMPLEMENT C2-DEPLETED SERUM, HUMAN complement C2 deficient serum 80295-40-5 BioChemical Biochemicals and Reagents Application Index Cell Signaling Enzymes Complement Deficient Sera Complement Proteins Enzymes, Inhibitors, and Substrates Cell Signaling Enzymes Complement Deficient Sera Complement Proteins