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BHPI

BHPI structure

CAS No.: 56632-39-4

Chemical Name:: BHPI

Synonyms: BHPI;CS-2134;1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one;2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-

CBNumber:: CB33041388

Molecular Formula:: C21H17NO3

Molecular Weight:: 331.36

MDL Number:

MOL File:: 56632-39-4.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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BHPI Properties

Melting point	272-274 °C
Boiling point	557.7±50.0 °C(Predicted)
Density	1.320±0.06 g/cm3(Predicted)
solubility	DMF: 5 mg/ml; DMSO: 11 mg/ml; Ethanol: 14 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
form	A crystalline solid
pka	9.43±0.30(Predicted)

BHPI price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	17750	BHPI ≥95%	56632-39-4	500μg	$57	2024-03-01	Buy
Cayman Chemical	17750	BHPI ≥95%	56632-39-4	1mg	$100	2024-03-01	Buy
Cayman Chemical	17750	BHPI ≥95%	56632-39-4	5mg	$412	2024-03-01	Buy
Tocris	6116	BHPI ≥98%(HPLC)	56632-39-4	50	$745	2021-12-16	Buy
Tocris	6116	BHPI ≥98%(HPLC)	56632-39-4	10	$177	2021-12-16	Buy

Product number	Packaging	Price	Buy
17750	500μg	$57	Buy
17750	1mg	$100	Buy
17750	5mg	$412	Buy
6116	50	$745	Buy
6116	10	$177	Buy

BHPI Chemical Properties,Uses,Production

Description

BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial, and ovarian cancer cell lines at concentrations ranging from 10 to 1,000 nM. It is effective in vivo, driving tumor regression in mice bearing MCF-7 xenografts at a dose of 15 mg/kg daily. BHPI specifically inhibits ERα-dependent gene expression and protein synthesis by activating the unfolded protein response in cells.

Uses

BHPI is an antagonist of estrogen receptor α (ERα) that blocks 17β-estradiol-induced proliferation of drug-resistant breast, endometrial and ovarian cancer cell lines.

storage

Store at -20°C

BHPI Preparation Products And Raw materials

Raw materials

Preparation Products

BHPI Suppliers

Global( 47)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7553	61
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Guangzhou QiYun Biotechnology Co., Ltd.	020-61288194 61288195	505721671@qq.com	China	3868	58
Musechem	+1-800-259-7612	info@musechem.com	United States	4662	60
Aikon International Limited	025-58859352 18068836627	sales01@aikonchem.com	China	15085	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9414	58
Cckinase, Inc.	+1 (732)236-3202	sales@cckinase.com	United States	2738	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Haoyuan Chemexpress Co., Ltd.	61
Shanghai EFE Biological Technology Co., Ltd.	58
Guangzhou QiYun Biotechnology Co., Ltd.	58
Musechem	60
Aikon International Limited	58
DC Chemicals	58
Cckinase, Inc.	58

BHPI 2H-Indol-2-one, 1,3-dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl- 1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one CS-2134 56632-39-4