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N-EPSILON-ACETYL-L-LYSINE

N-EPSILON-ACETYL-L-LYSINE Structure
N-EPSILON-ACETYL-L-LYSINE structure
CAS No.
692-04-6
Chemical Name:
N-EPSILON-ACETYL-L-LYSINE
Synonyms
H-LYS(AC)-OH;N-epsilon-acetyllysine;lys(ac);N6-Acetyllysine;N-EPSILON-ACETYL-L-LYS;NSC 102777;LYSINE(AC)-OH;H-L-LYS(AC)-OH;Nε-Ac-L-Lys-OH;Nε-Acetyllysine
CBNumber:
CB3308387
Molecular Formula:
C8H16N2O3
Molecular Weight:
188.22
MDL Number:
MFCD00002639
MOL File:
692-04-6.mol
Last updated:2023-05-18 11:31:03
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N-EPSILON-ACETYL-L-LYSINE Properties

Melting point 250 °C (dec.)(lit.)
Boiling point 323.23°C (rough estimate)
Density 1.1793 (rough estimate)
refractive index 1.4500 (estimate)
storage temp. -20°C
solubility Aqueous Base (Slightly), Water (Slightly)
form Powder
pka 2.53±0.24(Predicted)
color White
Water Solubility Soluble in water (miscible), and 80% acetic acid (50 mg/ml).
Sensitive Hygroscopic
InChIKey DTERQYGMUDWYAZ-ZETCQYMHSA-N
CAS DataBase Reference 692-04-6(CAS DataBase Reference)
FDA UNII 470AD5VY1X

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P280-P261
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  24/25-36-26
WGK Germany  3
HS Code  29241900

N-EPSILON-ACETYL-L-LYSINE price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A4021 Nω-Acetyl-L-lysine 692-04-6 1g $111 2024-03-01 Buy
Sigma-Aldrich A4021 Nω-Acetyl-L-lysine 692-04-6 5g $335 2024-03-01 Buy
TCI Chemical A2652 Nε-Acetyl-L-lysine >98.0%(T) 692-04-6 1g $51 2024-03-01 Buy
Alfa Aesar J64139 N(epsilon)-Acetyl-L-lysine, 99% 692-04-6 1g $56.65 2024-03-01 Buy
Alfa Aesar J64139 N(epsilon)-Acetyl-L-lysine, 99% 692-04-6 5g $195 2024-03-01 Buy
Product number Packaging Price Buy
A4021 1g $111 Buy
A4021 5g $335 Buy
A2652 1g $51 Buy
J64139 1g $56.65 Buy
J64139 5g $195 Buy

N-EPSILON-ACETYL-L-LYSINE Chemical Properties,Uses,Production

Description

Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-Llysine.
In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain.
Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines.
Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.

Chemical Properties

white crystalline powder

Uses

N-Epsilon-acetyl-l-lysine is used in the metabolomics study on the combined effect of cocaine and ethanol via liquid chromatography-mass spectrometry metabolomics approach.

Definition

ChEBI: An N6-acyl-L-lysine where the N6-acyl group is specified as acetyl.

Biochem/physiol Actions

Nε-Acetyl-L-lysine (L-AcK) is an R-chain N-acetylated α amino acid used together with other lysine analogues to differentiate and characterized various aminoacylases and regulator 2 (Sir2) enzymes/sirtuins.

N-EPSILON-ACETYL-L-LYSINE Preparation Products And Raw materials

Raw materials

Preparation Products

N-EPSILON-ACETYL-L-LYSINE Suppliers

Global( 149)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15928 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
GenicBio Limited 		+86-21-37621270 service@genicbio.com CHINA 991 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei xin bonus chemical co. LTD 		86-13657291602 linda@hubeijusheng.com CHINA 22968 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034 CHINA 3904 58
GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015 wuqiuyan@glschina.com China 2975 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
GenicBio Limited 		58
career henan chemical co 		58
Hubei xin bonus chemical co. LTD 		58
Chongqing Chemdad Co., Ltd 		58
CONIER CHEM AND PHARMA LIMITED 		58
GL Biochem (Shanghai) Ltd. 		58
GL Biochem(Binhai) Ltd. 		58

View Lastest Price from N-EPSILON-ACETYL-L-LYSINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
N-EPSILON-ACETYL-L-LYSINE pictures 2019-07-06 N-EPSILON-ACETYL-L-LYSINE
692-04-6
 US $1.00 / KG 1KG 99% 20kg Career Henan Chemical Co

N-EPSILON-ACETYL-L-LYSINE Spectrum

N-EPSILON-ACETYL-L-LYSINE(692-04-6)1HNMRN-EPSILON-ACETYL-L-LYSINE(692-04-6)IR1N-EPSILON-ACETYL-L-LYSINE(692-04-6)IR2N-EPSILON-ACETYL-L-LYSINE(692-04-6)Raman

692-04-6(N-EPSILON-ACETYL-L-LYSINE)Related Search:

Biocytin 5-Hydroxytryptophan (S)-2-amino-3-(4-(2-tert-butoxy-2-oxoethyl)phenyl)propanoic acid H-LYS(ALLOC)-OH H-L-Lys-NEt2.2HCl
H-Lys(Boc)-OBzl·HCl H-Lys(Boc)-OH H-L-Pen-OH.HCl.H2O H-L-Tyr-NEt2.HCl L-Phenylalanine, 4-cyclohexyl-
FMOC-LYS(PALMITOYL)-OH N-(3-MALEIMIDOPROPIONYL)BIOCYTIN N-EPSILON-ACETYL-L-LYSINE N-ALPHA-FMOC-N-EPSILON-ACETYL-L-LYSINE,FMOC-N-EPSILON-ACETYL-L-LYSINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-ACETYL-L-LYSINE N-6-Trifluoroacetyl-L-lysine
Fmoc-N-epsilon-trifluoroacetyl-L-lysine BOC-LYS(TFA)-OH FMOC-LYS(BIOTIN)-OH

1of4

N-E-ACETYL-L-LYSINE N-EPSILON-ACETYL-L-LYSINE H-L-LYS(AC)-OH (2S)-6-acetamido-2-amino-hexanoic acid LYSINE(AC)-OH Nε-Acetyllysine Nε-Ac-L-Lys-OH N-epsilon-Acetyl-L-lysine,99% 6-N-Acetyl-L-lysine-6-N-Acetyl-L-lysine-d8 (S)-6-acetaMido-2-aMinohexanoic acid Nε-Acetyl-L-lysine epsilon-Acetyl-L-lysine epsilon-N-Acetyllysine NSC 102777 omega-N-Acetyl-L-lysine -Acetyl-L-lysine Nε-Acetyl-L-lysine≥ 99% (HPLC) (2S)-2-amino-6-acetamidohexanoic acid L-Lysine, N6-acetyl- N-EPSILON-ACETYL-L-LYSINE USP/EP/BP N-epsilon-acetyl-laevo-lysine lys(ac) N6-Acetyllysine N-epsilon-acetyllysine H-LYS(AC)-OH N-EPSILON-ACETYL-L-LYS Lysine impurity 23 Lysine Impurity 10 Rabbit Anti-Acetylated Lysine antibody Mouse Anti-Acetylated Lysine antibody 692-04-6 CH3CONHCH24CHNH2CO2H Amino Acids and Peptides BioChemical Biochemicals and Reagents A - H Modified Amino Acids A - H Amino Acids Modified Amino Acids