ChemicalBook >> CAS DataBase List >>2,3,5,6-Tetrafluoropyridine

2,3,5,6-Tetrafluoropyridine

CAS No.
2875-18-5
Chemical Name:
2,3,5,6-Tetrafluoropyridine
Synonyms
2,3,5,6-TetrafL;2,3,5,6-TETRAFLUOROPYRIDINE;Pyridine,2,3,5,6-tetrafluoro-;2,3,5,6-Tetrafluoropyridine98%;2,3,5,6-Tetrafluoropyridine,99%;2,3,5,6-Tetrafluoropyridine 98%;N-TERT-BUTYL-ALPHA-(4-NITROPHENYL)- &;2,3,5,6-Tetrafluoropyridine ISO 9001:2015 REACH
CBNumber:
CB3444784
Molecular Formula:
C5HF4N
Molecular Weight:
151.06
MDL Number:
MFCD00011734
MOL File:
2875-18-5.mol
MSDS File:
SDS
Last updated:2024-04-02 17:31:45

2,3,5,6-Tetrafluoropyridine Properties

Boiling point 102 °C (lit.)
Density 1.499 g/mL at 25 °C (lit.)
refractive index n20/D 1.4046(lit.)
Flash point 87 °F
storage temp. Inert atmosphere,2-8°C
pka -10.94±0.20(Predicted)
form clear liquid
color Colorless to Light yellow
Specific Gravity 1.52
InChIKey HWIPMBCMGVXOKN-UHFFFAOYSA-N
CAS DataBase Reference 2875-18-5(CAS DataBase Reference)
NIST Chemistry Reference Pyridine, 2,3,5,6-tetrafluoro-(2875-18-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P210-P302+P352-P305+P351+P338
Hazard Codes  Xi,F,C
Risk Statements  10-36/37/38
Safety Statements  28-36
RIDADR  UN 1993 3/PG 3
WGK Germany  3
Hazard Note  Flammable/Irritant
HazardClass  3
PackingGroup  III
HS Code  29333990
NFPA 704
2
2 0

2,3,5,6-Tetrafluoropyridine price More Price(27)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 316679 2,3,5,6-Tetrafluoropyridine 95% 2875-18-5 1g $65.2 2023-06-20 Buy
TCI Chemical T1778 2,3,5,6-Tetrafluoropyridine >98.0%(GC) 2875-18-5 1g $48 2024-03-01 Buy
TCI Chemical T1778 2,3,5,6-Tetrafluoropyridine >98.0%(GC) 2875-18-5 5g $144 2024-03-01 Buy
Alfa Aesar B21905 2,3,5,6-Tetrafluoropyridine, 97% 2875-18-5 1g $41.1 2021-12-16 Buy
Alfa Aesar B21905 2,3,5,6-Tetrafluoropyridine, 97% 2875-18-5 5g $140 2021-12-16 Buy
Product number Packaging Price Buy
316679 1g $65.2 Buy
T1778 1g $48 Buy
T1778 5g $144 Buy
B21905 1g $41.1 Buy
B21905 5g $140 Buy

2,3,5,6-Tetrafluoropyridine Chemical Properties,Uses,Production

Synthesis

Catalytic reduction of aryl chlorides, bromides and iodides is well documented, however, aryl fluorides do not readily react under these conditions, owing to the strong C-F bond and the high activation barrier to bond breaking. Work in our laboratories showed that at high temperatures, pentafluoropyridine was converted to 2,3,5,6- tetrafluoropyridine using a palladium catalyst.
	2,3,5,6-Tetrafluoropyridine

Preparation

An autoclave sprayed with PTFE was charged with pentafluoropyridine (20.0 g,  118 mmol), HBr (32.0 g, 400 mmol) and sulpholane (40 cm3) and heated at 200 ℃ for  48 h. The mixture was added to water and extracted into ether. The ether solution was  shown to contain pentafluoropyridine (79%) and 2,3,5,6-tetrafluoropyridine (21%) by  comparison of their GCMS and fluorine nmr spectra with authentic samples.  

Description

Pyridine and its derivatives have been developed and utilized relatively early at home and abroad. It is widely used in medicine, pesticides, rubber, dyes and other fields. Since the 1960s, there have been hundreds of medicines, pesticides, dyes, and some special reagents developed with fluorine-containing aromatic compounds as intermediates. In the weakly basic pyridine ring, the nitrogen atom is more negatively charged, and then a fluorine atom with a strong electronegativity is introduced to synthesize a fluorine-containing pyridine intermediate.

Chemical Properties

clear colorless liquid

2402-79-1
2875-18-5
Synthesis of 2,3,5,6-Tetrafluoropyridine from 2,3,5,6-Tetrachloropyridine
Global( 289)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 16805 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Dongfan Chem. Co., Ltd.
021-34500607 13391355195 sales@dfanchem.com CHINA 61 55
Fluoropharm Co., Ltd.
+86-0571-85586753; +8613336034509 sales@fluoropharm.com China 1377 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
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0086-519-68231162 info@klongchem.com CHINA 131 58
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shandong chuangyingchemical Co., Ltd.
18853181302 sale@chuangyingchem.com CHINA 5909 58

Related articles

View Lastest Price from 2,3,5,6-Tetrafluoropyridine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,3,5,6-Tetrafluoropyridine pictures 2024-04-17 2,3,5,6-Tetrafluoropyridine
2875-18-5
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
	2,3,5,6-Tetrafluoropyridine pictures 2024-04-02 2,3,5,6-Tetrafluoropyridine
2875-18-5
US $5.00-0.20 / KG 1KG 98% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2,3,5,6-Tetrafluoropyridine pictures 2023-03-15 2,3,5,6-Tetrafluoropyridine
2875-18-5
US $0.00-0.00 / kg 1kg 98%Min 1000kg LY Global chemicals co.,ltd .
2,3,5,6-TETRAFLUOROPYRIDINE 2,3,5,6-Tetrafluoropyridine 98% 2,3,5,6-Tetrafluoropyridine98% 2,3,5,6-Tetrafluoropyridine,99% N-TERT-BUTYL-ALPHA-(4-NITROPHENYL)- & Pyridine,2,3,5,6-tetrafluoro- 2,3,5,6-TetrafL 2,3,5,6-Tetrafluoropyridine ISO 9001:2015 REACH 2875-18-5 2875-18-8 C5HF4N Fluoropyridines C5 Building Blocks Pyridines Heterocyclic Building Blocks Halopyridines Fluorine series Pyridine Heterocyclic Compounds Fluoropyridines Halopyridines C5 Heterocyclic Building Blocks Pyridines