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2,3-DINOR PROSTAGLANDIN E1

2,3-DINOR PROSTAGLANDIN E1 Structure
2,3-DINOR PROSTAGLANDIN E1 structure
CAS No.
7046-40-4
Chemical Name:
2,3-DINOR PROSTAGLANDIN E1
Synonyms
2,3-dinor PGE1;2,3-DINOR PROSTAGLANDIN E1;2,3-dinor Prostaglandin E?;GTUGBRJEKVKOKQ-LRSAKWJDSA-N;2,3-dinor Prostaglandin E1;9-oxo-11α,15S-dihydroxy-2,3-dinor-prost-13E-en-1-oic acid;9-OXO-11ALPHA,15S-DIHYDROXY-2,3-DINOR-PROST-13E-EN-1-OIC ACID;Cyclopentanepentanoic acid, 3-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-5-oxo-, (1R,2R,3R)-
CBNumber:
CB3749665
Molecular Formula:
C18H30O5
Molecular Weight:
326.43
MDL Number:
MFCD03411990
MOL File:
7046-40-4.mol
Last updated:2023-06-08 09:03:09
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2,3-DINOR PROSTAGLANDIN E1 Properties

Boiling point 508.6±50.0 °C(Predicted)
Density 1.164±0.06 g/cm3(Predicted)
solubility DMF: >100 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS (pH 7.2): 1.67 mg/ml
pka 4.75±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H319
Precautionary statements  P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P337+P313-P370+P378-P403+P235-P501
NFPA 704
3
2 0

2,3-DINOR PROSTAGLANDIN E1 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 13120 2,3-dinor Prostaglandin E1 ≥98% 7046-40-4 25μg $57 2024-03-01 Buy
Cayman Chemical 13120 2,3-dinor Prostaglandin E1 ≥98% 7046-40-4 50μg $107 2024-03-01 Buy
Cayman Chemical 13120 2,3-dinor Prostaglandin E1 ≥98% 7046-40-4 100μg $198 2024-03-01 Buy
American Custom Chemicals Corporation CCH0006022 2,3-DINOR PROSTAGLANDIN E1 95.00% 7046-40-4 5MG $504.16 2021-12-16 Buy
Product number Packaging Price Buy
13120 25μg $57 Buy
13120 50μg $107 Buy
13120 100μg $198 Buy
CCH0006022 5MG $504.16 Buy

2,3-DINOR PROSTAGLANDIN E1 Chemical Properties,Uses,Production

Description

Prostaglandin E1 (PGE1) is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction and in neonatal cardiology.1,2 The metabolism of PGE1 is normally initiated by oxidation at C-15, resulting in 13,14-dihydro-15-keto PGE1 as the major metabolite. However, inhibition of this pathway or saturation by excess substrate could theoretically lead to enhanced production of 2,3-dinor metabolites, including 2,3-dinor PGE1. The biological activity of 2,3-dinor PGE1 has not been published. Cayman Chemical is a leading supplier of prostaglandins and their metabolites, and is currently the exclusive manufacturer of 2,3-dinor PGE1.

Definition

ChEBI: 2,3-Dinor-PGE1 is a prostanoid.

References

1. Virag, R., Shoukry, K., Floresco, J., et al. Intracavernous self-injection of vasoactive drugs in the treatment of impotence: 8-Year experience with 615 cases J. Urol. 145(2),287-293(1991).
2. Hoshi, K. Approved indications of lipo-PGE1 in Japan Adv. Drug Deliv. Rev. 20(2-3),171-176(1996).

2,3-DINOR PROSTAGLANDIN E1 Preparation Products And Raw materials

Raw materials

Preparation Products

2,3-DINOR PROSTAGLANDIN E1 Suppliers

Global( 15)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 55827 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1991 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48570 58
Supplier Advantage
Aladdin Scientific 		58
ChemStrong Scientific Co.,Ltd 56
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58

7046-40-4(2,3-DINOR PROSTAGLANDIN E1)Related Search:

Prostaglandin E1 2,3-DINOR PROSTAGLANDIN E1
9-OXO-11ALPHA,15S-DIHYDROXY-2,3-DINOR-PROST-13E-EN-1-OIC ACID 2,3-dinor Prostaglandin E1 2,3-DINOR PROSTAGLANDIN E1 GTUGBRJEKVKOKQ-LRSAKWJDSA-N 9-oxo-11α,15S-dihydroxy-2,3-dinor-prost-13E-en-1-oic acid 2,3-dinor PGE1 Cyclopentanepentanoic acid, 3-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-5-oxo-, (1R,2R,3R)- 2,3-dinor Prostaglandin E? 7046-40-4