URSODEOXYCHOLIC-2,2,4,4-D4 ACID
- CAS No.
- 347841-46-7
- Chemical Name:
- URSODEOXYCHOLIC-2,2,4,4-D4 ACID
- Synonyms
- Ursodeoxycholic-d4 Acid;2H4]-Ursodeoxycholic Acid;URSODEOXYCHOLIC-2,2,4,4-D4 ACID;Urosodeoxycholic Acid Impurity 28;Ursodeoxycholic acid-[d4] (Solution);Ursodiol-d4 (Ursodeoxycholic Acid-d4);Ursodeoxycholic Acid-2,2,4,4-d4 (Major);Ursodeoxycholic Acid-d4 MaxSpec? Standard;*Dronedarone Impurity 37 ( Tributylamine);URSODEOXYCHOLIC ACID (2,2,4,4-D4, 98%) 95% CHEMICAL PURITY
- CBNumber:
- CB3755802
- Molecular Formula:
- C24H40O4
- Molecular Weight:
- 392.58
- MDL Number:
- MFCD01317390
- MOL File:
- 347841-46-7.mol
- MSDS File:
- SDS
URSODEOXYCHOLIC-2,2,4,4-D4 ACID price More Price(7)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 21892 | Ursodeoxycholic Acid-d4 ≥99% deuterated forms (d1-d4) | 347841-46-7 | 500μg | $73 | 2024-03-01 | Buy |
| Cayman Chemical | 21892 | Ursodeoxycholic Acid-d4 ≥99% deuterated forms (d1-d4) | 347841-46-7 | 1mg | $138 | 2024-03-01 | Buy |
| Cayman Chemical | 21892 | Ursodeoxycholic Acid-d4 ≥99% deuterated forms (d1-d4) | 347841-46-7 | 5mg | $575 | 2024-03-01 | Buy |
| Medical Isotopes, Inc. | D2127 | Ursodeoxycholic-2,2,4,4-d4acid | 347841-46-7 | 5mg | $590 | 2021-12-16 | Buy |
| IsoSciences | 13102 | UrsodeoxycholicAcid-[d4] ≥95% | 347841-46-7 | 50mg | $288 | 2021-12-16 | Buy |
URSODEOXYCHOLIC-2,2,4,4-D4 ACID Chemical Properties,Uses,Production
Description
Ursodeoxycholic acid-d4 (UDCA-d4) is intended for use as an internal standard for the quantification of UDCA (Item No. 15121) by GC- or LC-MS. UDCA is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.
Uses
Ursodeoxycholic Acid-d4 is a deuterated form of Ursodeoxcholic Acid (U850000), which is used as an anticholelithogenic. Ursodeoxcholic Acid is an epimer with Chenodiol with respect to the hydroxyl group at C7. Ursodeoxycholic Acid-d4 was used as an internal standard for rapid quantification of bile acids by liquid chromatography-tandem mass spectrometry.
URSODEOXYCHOLIC-2,2,4,4-D4 ACID Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 4975 | 50 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
| ChemStrong Scientific Co.,Ltd | 0755-0755-66853366 13670046396 | sales@chem-strong.com | China | 17982 | 56 |
| Artis Biotech Co. Ltd. | 19138486554 18582380095 | sales@artisbio.com | China | 3066 | 58 |
| Chengdu Novel Biomedical Co., Ltd. | 028-85255396 18302801538 | cdnovell@163.com | China | 2238 | 58 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 02584622273; | kexin.zhou@haolvbiotech.com | China | 3021 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | rose.shi@synzest.com | China | 9287 | 58 |
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