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6-Nitrophthalide

CAS No.
610-93-5
Chemical Name:
6-Nitrophthalide
Synonyms
NSC 11332;AKOS 237-80;6-NITROPHTALIDE;6-NITROPHTHALIDE;BUTTPARK 33\04-92;RARECHEM AR PA 0038;6-Nitrophthalide,97%;6-Nitrophthalide, 97% 1GR;6-nitro-3H-2-benzofuran-1-one;6-Nitroisobenzofuran-1(3H)-one
CBNumber:
CB3769045
Molecular Formula:
C8H5NO4
Molecular Weight:
179.13
MDL Number:
MFCD00033529
MOL File:
610-93-5.mol
Last updated:2023-04-23 13:52:06

6-Nitrophthalide Properties

Melting point 140-145 °C(lit.)
Boiling point 311.63°C (rough estimate)
Density 1.4908 (rough estimate)
refractive index 1.5160 (estimate)
storage temp. Sealed in dry,Room Temperature
form Crystalline Powder
color Pale yellow
Water Solubility 0.4g/L(25 ºC)
CAS DataBase Reference 610-93-5(CAS DataBase Reference)
FDA UNII 35QB7T32YC

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  20/21/22-36/37/38
Safety Statements  24/25-37-26
WGK Germany  3
HazardClass  IRRITANT
HS Code  29322090
NFPA 704
1
2 0

6-Nitrophthalide price More Price(38)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical N1055 6-Nitrophthalide >95.0%(GC) 610-93-5 1g $25 2024-03-01 Buy
TCI Chemical N1055 6-Nitrophthalide >95.0%(GC) 610-93-5 5g $84 2024-03-01 Buy
Alfa Aesar B20375 6-Nitrophthalide, 97% 610-93-5 5g $72.65 2024-03-01 Buy
Alfa Aesar B20375 6-Nitrophthalide, 97% 610-93-5 1g $22 2021-12-16 Buy
Alfa Aesar B20375 6-Nitrophthalide, 97% 610-93-5 25g $279.65 2024-03-01 Buy
Product number Packaging Price Buy
N1055 1g $25 Buy
N1055 5g $84 Buy
B20375 5g $72.65 Buy
B20375 1g $22 Buy
B20375 25g $279.65 Buy

6-Nitrophthalide Chemical Properties,Uses,Production

Chemical Properties

pale yellow crystalline powder

Uses

6-Nitrophthalide is a fluorescent heterocycle that can be used as a probe for specific inhibition. It is homologous to other fluorescent probes such as fluorescein, nitrobenzene, and nitrophenol. It has been shown to have inhibitory properties against triazole and dipole, which are catalytic asymmetric. 6-Nitrophthalide has also been shown to have the ability to inhibit the oxidation of aldehydes.

Preparation

6-Nitrophthalide is synthesized from 2-nitrobenzaldehyde via a two-step process, and then reacted with methyl iodide.

Application

6-Nitrophthalide has been used in the preparation of 3-bromo-6-nitrophthalide. It undergoes reductive methylation to form 6-dimethylaminophthalide.

85-44-9
610-93-5
Synthesis of 6-Nitrophthalide from Phthalic anhydride
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RARECHEM AR PA 0038 6-NITRO-1,3-DIHYDROISOBENZOFURAN-1-ONE 6-NITRO-3H-ISOBENZOFURAN-1-ONE 6-NITROPHTALIDE 6-NITROPHTHALIDE BUTTPARK 33\04-92 6-Nitrophthalide,97% AKOS 237-80 6-Nitrophthalide, 97% 1GR 6-nitro-3H-2-benzofuran-1-one 6-Nitroisobenzofuran-1(3H)-one 6-Nitro-1(3H)-isobenzofuranone NSC 11332 2-[(E)-2-(4-quinolinyl)ethenyl]aniline 1(3H)-Isobenzofuranone, 6-nitro- 610-93-5 O2NC6H3COOCH2 Lactones Organic Building Blocks Carbonyl Compounds Building Blocks Phthalides Carbonyl Compounds Lactones Organic Building Blocks