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1H-Indole-6-acetamide, N-(3-hydroxyphenyl)-

CAS No.
1787787-60-3
Chemical Name:
1H-Indole-6-acetamide, N-(3-hydroxyphenyl)-
Synonyms
AIM2-IN-3;NLRP3/AIM2-IN-3;1H-Indole-6-acetamide, N-(3-hydroxyphenyl)-
CBNumber:
CB410724046
Molecular Formula:
C16H14N2O2
Molecular Weight:
266.29
MDL Number:
MOL File:
1787787-60-3.mol
Last updated:2023-05-21 10:59:17

1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Properties

Boiling point 608.2±45.0 °C(Predicted)
Density 1.372±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (938.83 mM; Need ultrasonic)
pka 9.54±0.10(Predicted)

1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Chemical Properties,Uses,Production

Biological Activity

NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of NLRP3 and AIM2 inflammatory bodies and has species differences. Its IC 50 value is 0.077 ± 0.008 μ M。

References

[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.

1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Raise Chemical Technology Co.,Ltd 15026594951 rs@raise-chem.com China 3204 55
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24023 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 sales@szzxbio.com China 3001 58
1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- AIM2-IN-3 NLRP3/AIM2-IN-3 1787787-60-3