| Company Name: |
Jinan Jiuli Biotechnology Co. , Ltd.
|
| Tel: |
2717893647 14768611851 |
| Email: |
486064515@qq.com |
| Products Intro: |
Product Name:NLRP3/AIM2-IN-3
CAS:1787787-60-3
Purity:98% Package:500mg；1g；5g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:NLRP3/AIM2-IN-3
CAS:1787787-60-3
Purity:98% Package:500 mg
|
|
| | 1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Basic information |
| | 1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Chemical Properties |
| Boiling point | 608.2±45.0 °C(Predicted) | | density | 1.372±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 250 mg/mL (938.83 mM; Need ultrasonic) | | pka | 9.54±0.10(Predicted) |
| | 1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Usage And Synthesis |
| Biological Activity | NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of NLRP3 and AIM2 inflammatory bodies and has species differences. Its IC 50 value is 0.077 ± 0.008 μ M。 | | References | [1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194. |
| | 1H-Indole-6-acetamide, N-(3-hydroxyphenyl)- Preparation Products And Raw materials |
|