Dexamethasone palmitate
- CAS No.
- 14899-36-6
- Chemical Name:
- Dexamethasone palmitate
- Synonyms
- D01615;Lipotalon;Limethason;Limethasone;Limethason (tn);DXM-21-palmitate;DEXAMETHASOME PALMITATE;Dexamethasone palmitate;Dexamethasone-21-palmitate;Dexamethasone palmitate (jan)
- CBNumber:
- CB41074390
- Molecular Formula:
- C38H59FO6
- Molecular Weight:
- 630.87
- MDL Number:
- MOL File:
- 14899-36-6.mol
| Melting point | 60-65 °C |
|---|---|
| Boiling point | 710.1±60.0 °C(Predicted) |
| Density | 1.12 |
| storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) |
| pka | 11.99±0.70(Predicted) |
| form | Solid |
| color | White to Pale Yellow |
| Stability | Hygroscopic |
| FDA UNII | 601XWN7060 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501 | |||||||||
| NFPA 704 |
|
Dexamethasone palmitate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | D298830 | Dexamethasone21-Palmitate | 14899-36-6 | 250mg | $480 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21400 | Dexamethasone 21-palmitate | 14899-36-6 | 250mg | $700 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0012845 | DEXAMETHASONE PALMITATE 95.00% | 14899-36-6 | 100MG | $721.88 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD21400 | Dexamethasone 21-palmitate | 14899-36-6 | 500mg | $1200 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0012845 | DEXAMETHASONE PALMITATE 95.00% | 14899-36-6 | 1G | $1732.5 | 2021-12-16 | Buy |
Dexamethasone palmitate Chemical Properties,Uses,Production
Description
Dexamethasone palmitate (DXP) is a prodrug of dexamethasone,which is a steroidal antinflammatory drug that is used to treat certain pain and inflammatory conditions such as asthma and rheumatoid arthritis. This prodrug was prepared to increase the distribution of the parent drug, dexamethasone, in the lungs for local drug delivery and to prevent its entry into the systemic circulation. This prodrug was developed as a powder formulation that needs to be administered via the pulmonary route so that it can easily reach into the lungs and show its effect locally.Normal delivery of dexamethasone enters systemic circulation very easily but this palmitate prodrug cannot easily enter into the systemic circula-tion. Within the lungs, the prodrug is acted upon by esterase enzyme that brings about hydrolysis,leading to the release of parent drug and increases the distribution of parentdrug inside the lungs (N'Guessan et al.,2018).
Chemical Properties
Colourless Thick Oil
Uses
A corticosteroid prodrug for the treatment of eye disorders.
Definition
ChEBI: Dexamethasone palmitate is an organic molecular entity.
Biochem/physiol Actions
Dexamethasone Palmitate is a lipophilic prodrug of a potent corticosteroid dexamethasone that is quickly taking up by macrophages via phagocytosis. Dexamethasone Palmitate inhibits function and migration of leukocytes and tissue macrophages.
Dexamethasone palmitate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
View Lastest Price from Dexamethasone palmitate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-29 | Dexamethasone palmitate
14899-36-6
|
US $0.00-0.00 / KG | 1KG | 99% | 5000 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2022-12-24 | Dexamethasone palmitate
14899-36-6
|
US $0.00-0.00 / KG | 1KG | 99% | 100000000000 | Hubei Harvest Chemical CO.,Ltd | |
 |
2019-07-06 | Dexamethasone palmitate
14899-36-6
|
US $1.00 / KG | 1KG | 98% | 100KG | Career Henan Chemical Co |
-
- Dexamethasone palmitate
14899-36-6
- US $0.00-0.00 / KG
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Dexamethasone palmitate
14899-36-6
- US $0.00-0.00 / KG
- 99%
- Hubei Harvest Chemical CO.,Ltd
-
- Dexamethasone palmitate
14899-36-6
- US $1.00 / KG
- 98%
- Career Henan Chemical Co
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