Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>15(S)-HETRE

15(S)-HETRE

15(S)-HETRE Structure
15(S)-HETRE structure
CAS No.
92693-02-2
Chemical Name:
15(S)-HETRE
Synonyms
15(S)-HETRE;15(S) HETrE,15(S)HETrE;IUKXMNDGTWTNTP-OAHXIXLCSA-N;15S-HYDROXY-8Z,11Z,13E-EICOSATRIENOIC ACID;15(S)-HYDROXYEICOSA-8Z, 11Z, 13E-TRIENOIC ACID;8,11,13-Eicosatrienoic acid, 15-hydroxy-, (8Z,11Z,13E,15S)-
CBNumber:
CB4110282
Molecular Formula:
C20H34O3
Molecular Weight:
322.48
MDL Number:
MFCD00084835
MOL File:
92693-02-2.mol
Last updated:2023-05-21 10:59:17
Request For Quotation

15(S)-HETRE Properties

Boiling point 487.4±40.0 °C(Predicted)
Density 0.971±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml
pka 4.77±0.10(Predicted)

15(S)-HETRE price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 36720 15(S)-HETrE ≥98% 92693-02-2 25μg $79 2024-03-01 Buy
Cayman Chemical 36720 15(S)-HETrE ≥98% 92693-02-2 50μg $150 2024-03-01 Buy
Cayman Chemical 36720 15(S)-HETrE ≥98% 92693-02-2 100μg $280 2024-03-01 Buy
Cayman Chemical 36720 15(S)-HETrE ≥98% 92693-02-2 500μg $623 2024-03-01 Buy
Product number Packaging Price Buy
36720 25μg $79 Buy
36720 50μg $150 Buy
36720 100μg $280 Buy
36720 500μg $623 Buy

15(S)-HETRE Chemical Properties,Uses,Production

Description

15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of dihomo-γ-linolenic acid (DGLA; ). It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 μM.1 In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.2

References

1. Petrich, K., Ludwig, P., Kühn, H., et al. The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leukocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: Structure-activity relationship and mechanism of action Biochem. J. 314,911-916(1996).
2. Haviv, F., Ratajczyk, J.D., DeNet, R.W., et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues J. Med. Chem. 30(2),254-263(1987).

15(S)-HETRE Preparation Products And Raw materials

Raw materials

Preparation Products

15(S)-HETRE Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
BOC Sciences -- info@bocsci.com USA 0 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
amyjetsci 027-59626688 18771149750 sales@amyjet.com China 3004 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24018 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7984 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48467 58
Supplier Advantage
Aladdin Scientific 		58
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 65
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
MedBioPharmaceutical Technology Inc 58
amyjetsci 58
TargetMol Chemicals Inc. 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
15(S)-HETRE 15S-HYDROXY-8Z,11Z,13E-EICOSATRIENOIC ACID 15(S)-HYDROXYEICOSA-8Z, 11Z, 13E-TRIENOIC ACID IUKXMNDGTWTNTP-OAHXIXLCSA-N 15(S) HETrE,15(S)HETrE 8,11,13-Eicosatrienoic acid, 15-hydroxy-, (8Z,11Z,13E,15S)- 92693-02-2