2-Iodophenol
- CAS No.
- 533-58-4
- Chemical Name:
- 2-Iodophenol
- Synonyms
- O-IODOPHENOL;ORTHO-IODOPHENOL;DK807;NSC 9245;o-Jodfenol;2-Jodfenol;2-iodo-pheno;2-IODOPHENOL;o-iodo-pheno;2-lodophenol
- CBNumber:
- CB4130718
- Molecular Formula:
- C6H5IO
- Molecular Weight:
- 220.01
- MDL Number:
- MFCD00013963
- MOL File:
- 533-58-4.mol
- MSDS File:
- SDS
Melting point | 37-40 °C (lit.) |
---|---|
Boiling point | 186-187 °C/160 mmHg (lit.) |
Density | 1.947 g/mL at 25 °C (lit.) |
Flash point | >230 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
form | Crystalline Powder or Crystalline Low Melting Mass |
pka | 8.51(at 25℃) |
color | White or cream to brown |
Specific Gravity | 1.947 |
Water Solubility | slightly soluble |
Sensitive | Light Sensitive |
Merck | 14,5035 |
BRN | 1855300 |
Stability | Stable. Incompatible with strong oxidizing agents. |
InChIKey | KQDJTBPASNJQFQ-UHFFFAOYSA-N |
CAS DataBase Reference | 533-58-4(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | F27L34A8B9 |
NIST Chemistry Reference | Phenol, 2-iodo-(533-58-4) |
EPA Substance Registry System | Phenol, 2-iodo- (533-58-4) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332-H315-H319-H335 | |||||||||
Precautionary statements | P261-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 20/21/22-36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | SL5500000 | |||||||||
TSCA | T | |||||||||
HazardClass | IRRITANT, LIGHT SENSITIVE | |||||||||
HS Code | 29081000 | |||||||||
NFPA 704 |
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2-Iodophenol price More Price(44)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 281409 | 2-Iodophenol 98% | 533-58-4 | 5g | $60.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 281409 | 2-Iodophenol 98% | 533-58-4 | 25g | $121 | 2024-03-01 | Buy |
TCI Chemical | I0460 | 2-Iodophenol >99.0%(GC) | 533-58-4 | 5g | $41 | 2024-03-01 | Buy |
TCI Chemical | I0460 | 2-Iodophenol >99.0%(GC) | 533-58-4 | 25g | $134 | 2024-03-01 | Buy |
Alfa Aesar | A13599 | 2-Iodophenol, 98% | 533-58-4 | 5g | $34.65 | 2024-03-01 | Buy |
2-Iodophenol Chemical Properties,Uses,Production
Chemical Properties
colorless needle-like crystals or Pale Yellow Low Melting Solid. Slightly soluble in water, easily soluble in organic solvents such as ethanol and ether.
Uses
2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.
Definition
ChEBI: 2-iodophenol is a 2-halophenol and an iodophenol.
Application
2-Iodophenol is a halophenol with antifungal activity. 2-Iodophenol was used in the synthesis of:
aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity
3,3-disubstituted-2,3-dihydrobenzofurans
1,3,5-substituted benzenes.
2-Iodophenol is also used as additive tracers for resist plasm a etching and suzuki reaction.
Preparation
synthesis of 2-iodophenol: phenol (1a) to react with 0.5 equivalent of iodine and 1 equivalent of hydrogen peroxide in water at room temperature for 24 h, 2,6-diiodophenol (2a) and 2-iodophenol (3) were isolated in yields of 21 and 49%, respectively.
Synthesis Reference(s)
The Journal of Organic Chemistry, 53, p. 5281, 1988 DOI: 10.1021/jo00257a014
General Description
Rapid palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with various alkyne under microwave irradiation using Mo(CO)6 as the CO source has been investigated.
Purification Methods
Crystallise 2-iodophenol from CHCl3 or diethyl ether. The acetate has m 65-66o (from MeOH). [Beilstein 6 H 208, 6 II 198, 6 III 774, 6 IV 1074.]
2-Iodophenol Preparation Products And Raw materials
Raw materials
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Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20291 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21666 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 7621 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
View Lastest Price from 2-Iodophenol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-23 | 2-Iodophenol
533-58-4
|
US $30.00-10.00 / kg | 10kg | 99% | 100000kg | Hebei Chuanghai Biotechnology Co,.LTD | ||
2023-12-24 | 2-Iodophenol
533-58-4
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-04-28 | 2-Iodophenol
533-58-4
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Guanlang Biotechnology Co., Ltd. |
- 2-Iodophenol
533-58-4
- US $30.00-10.00 / kg
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
- 2-Iodophenol
533-58-4
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- 2-Iodophenol
533-58-4
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.