CREBtide
- CAS No.
- 149155-45-3
- Chemical Name:
- CREBtide
- Synonyms
- CREBtide TFA;L-Arginine, L-lysyl-L-arginyl-L-arginyl-L-α-glutamyl-L-isoleucyl-L-leucyl-L-seryl-L-arginyl-L-arginyl-L-prolyl-L-seryl-L-tyrosyl-
- CBNumber:
- CB41319905
- Molecular Formula:
- C73H129N29O19
- Molecular Weight:
- 1716.99
- MDL Number:
- MOL File:
- 149155-45-3.mol
CREBtide price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alfa Aesar | J66434 | CREBtide | 149155-45-3 | 0.5mg | $131 | 2023-06-20 | Buy |
Alfa Aesar | J66434 | CREBtide | 149155-45-3 | 1mg | $192 | 2023-06-20 | Buy |
ChemScene | CS-0045222 | CREBtide | 149155-45-3 | 5mg | $280 | 2021-12-16 | Buy |
ChemScene | CS-0045222 | CREBtide | 149155-45-3 | 10mg | $440 | 2021-12-16 | Buy |
ChemScene | CS-0045222 | CREBtide | 149155-45-3 | 1mg | $80 | 2021-12-16 | Buy |
CREBtide Chemical Properties,Uses,Production
Biological Activity
CREBtide is a synthetic 13 amino acid peptide that acts as a PKA substrate.
in vitro
delta-CREB is a spliced variant of cAMP response element binding protein (CREB). CREBtide (KRREILSRRPSYR), a synthetic peptide based on the phosphorylation sequence in delta-CREB. delta-CREB and CREBtide are tested as substrates of cAMP-dependent protein kinase (cAK). The apparent K m of CREBtide phosphorylation by cAK is 3.9 μM, which is 10-fold lower than that of Kemptide (K m =39 μM), the synthetic peptide substrate most often employed for cAK measurement. The V max values are 12.4 mumol/(min.mg) for CREBtide and 9.8 mumol/(min.mg) for Kemptide. The apparent K m of CREBtide phosphorylation by cGMP-dependent protein kinase (cGK) is 2.9 μM and the V max value is 3.2 mumol/(min.mg). Both delta -CREB and CREBtide are phosphorylated at a much slower rate by cGK as compared with cAK, implying that the high cAK/cGK specificity exhibits by delta-CREB is retained by the peptide.
target
PKA
CREBtide Preparation Products And Raw materials
Raw materials
Preparation Products
CREBtide Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
BOC Sciences | 16314854226; +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
Creative Peptides | info@creative-peptides.com | United States | 6084 | 56 | |
Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 | eric@peptidego.com | China | 6527 | 58 |
Nanchang Tianzhen Biotechnology Co., Ltd | 13173652190 | pomy@tanzhenbio.com | China | 1618 | 58 |
Wuxi Helen Biotechnology Co., Ltd., | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 14092 | 58 |
Ontores Biotech | 0571-88760729 18072970094 | supports@ontorespeptide.com | China | 2696 | 58 |