safracin B
- CAS No.
- 87578-99-2
- Chemical Name:
- safracin B
- Synonyms
- safracin B;Antibiotic EM 5519;Antibiotic Y 16482-alpha;2-Amino-N-[(6,7,9,10,13,14,14a,15-octahydro-1,7-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-epimino-5H-isoquino[3,2-b][3]benzazocin-9-yl)methyl]propionamide;Propanamide, 2-amino-N-[[(6S,7S,9R,14aS,15R)-6,7,9,10,13,14,14a,15-octahydro-1,7-dihydroxy-2,11-dimethoxy-3,12,16-trimethyl-10,13-dioxo-6,15-imino-5H-isoquino[3,2-b][3]benzazocin-9-yl]methyl]-, (2S)-
- CBNumber:
- CB41353031
- Molecular Formula:
- C28H36N4O7
- Molecular Weight:
- 540.61
- MDL Number:
- MFCD01939882
- MOL File:
- 87578-99-2.mol
- MSDS File:
- SDS
| Boiling point | 755.1±60.0 °C(Predicted) |
|---|---|
| Density | 1.41±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in DMSO (up to 20 mg/ml) |
| form | solid |
| pka | 9.75±0.70(Predicted) |
| color | Yellow-green |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H312 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P302+P352-P321-P332+P313-P362-P280-P302+P352-P312-P322-P363-P501 |
safracin B Chemical Properties,Uses,Production
Description
Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by?Pseudomonas fluorescens.1?Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2
Uses
Safracin B is a new antibiotics from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B is an antibiotic that exhibits anti-tumor properties.
References
1) Ikeda?et al.?(1983),?Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo,?36?1279 2) Okumoto?et al. (1985),?Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo,?38?767
safracin B Preparation Products And Raw materials
Raw materials
Preparation Products
safracin B Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| AB PharmaTech,LLC | 323-480-4688 | United States | 989 | 55 | |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10248 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| BOC Sciences | +16314854226 | inquiry@bocsci.com | United States | 19743 | 58 |
| ATK CHEMICAL COMPANY LIMITED | 3429815786 13301662590 | sales@atkchemical.com | China | 10006 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9445 | 58 |
| Nanjing Meihao Pharmaceutical Technology Co., Ltd. | meitaochem@126.com | meitaochem@126.com | China | 19105 | 58 |
| Beijing xinyanhui pharmaceutical research and development co., LTD | 13969155946 | 1461866103@qq.com | China | 16111 | 58 |
| Shanghai Jiegu Biotechnology Co., Ltd. | 021-51698675 | jiejiegroup@126.com | China | 4112 | 58 |
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