ChemicalBook >> CAS DataBase List >>CYCLO(-LEU-PRO)

CYCLO(-LEU-PRO)

CYCLO(-LEU-PRO) structure

CAS No.: 2873-36-1

Chemical Name:: CYCLO(-LEU-PRO)

Synonyms: gancidinw;Maculosin 6;Cyclo(Pro-Leu);CYCLO(-LEU-PRO);cyclo-l-leu-l-pro;Cyclo(L-Pro-D-Leu);Cyclo(L-Pro-L-Leu-);Cyclo(proline-leucine);Cyclo-L-prolyl-L-leucine;L-Leucyl-L-prolyl lactaM

CBNumber:: CB4142038

Molecular Formula:: C11H18N2O2

Molecular Weight:: 210.27

MDL Number:: MFCD00237617

MOL File:: 2873-36-1.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:20

Request For Quotation

CYCLO(-LEU-PRO) Properties

Melting point	163-165℃
Boiling point	427.6±34.0 °C(Predicted)
Density	1.14
storage temp.	Inert atmosphere,2-8°C
solubility	Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly)
form	Solid
pka	13.27±0.40(Predicted)
color	White to Off-White
FDA UNII	KQV8MY059B

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H317
Precautionary statements	P280
Toxicity	mouse,LD50,intravenous,80mg/kg (80mg/kg),"Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978Vol. 2, Pg. 1354, 1978.

CYCLO(-LEU-PRO) price More Price(16)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	24941	Cyclo(L-Leu-L-Pro) ≥95%	2873-36-1	5mg	$128	2024-03-01	Buy
Cayman Chemical	24941	Cyclo(L-Leu-L-Pro) ≥95%	2873-36-1	25mg	$383	2024-03-01	Buy
TRC	C987660	Cyclo(L-prolyl-L-leucyl)	2873-36-1	25mg	$425	2021-12-16	Buy
American Custom Chemicals Corporation	PEP0007072	CYCLO(L-LEU-L-PRO) 95.00%	2873-36-1	5MG	$650	2021-12-16	Buy
Medical Isotopes, Inc.	63838	Cyclo(L-prolyl-L-leucyl)	2873-36-1	10mg	$650	2021-12-16	Buy

Product number	Packaging	Price	Buy
24941	5mg	$128	Buy
24941	25mg	$383	Buy
C987660	25mg	$425	Buy
PEP0007072	5MG	$650	Buy
63838	10mg	$650	Buy

CYCLO(-LEU-PRO) Chemical Properties,Uses,Production

Description

Cyclo(L-Leu-L-Pro) is a diketopiperazine metabolite that has been isolated from various bacterial and fungal species including Streptomyces. It is active against twelve strains of vancomycin-resistant enterococci (VRE) with MIC values of 12.5 μg/ml for E. faecalis strains K-99-34, K-00-184, and K-00-221. It also inhibits growth of K562, HL-60, and U937 leukemia cells in a concentration-dependent manner when used at concentrations of 1-500 μg/ml. Cyclo(L-Leu-L-Pro) also has antifouling activity, inhibiting attachment of B. amphitrite larva with an EC₅₀ value of 0.15 mM.

Chemical Properties

White Solid

Uses

Sorbicillin analog. A bioactive secondary metabolites from terrestrial Streptomyces species TN262.

Definition

ChEBI: A homodetic cyclic peptide composed from leucyl and prolyl residues.

CYCLO(-LEU-PRO) Preparation Products And Raw materials

Raw materials

Preparation Products

CYCLO(-LEU-PRO) Suppliers

Global( 84)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Finetech Industry Limited	+86-27-87465837 +8618971612321	info@finetechnology-ind.com	China	9651	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19915	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9821	58
Chengdu Youngshe Chemical Co., Ltd.	+8618108235634	Cecilia@youngshechem.com	China	2345	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58

Supplier	Advantage
career henan chemical co	58
BOC Sciences	58
Chongqing Chemdad Co., Ltd	58
CONIER CHEM AND PHARMA LIMITED	58
Finetech Industry Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
Nextpeptide Inc	58
changzhou huayang technology co., ltd	58
Chengdu Youngshe Chemical Co., Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58

View Lastest Price from CYCLO(-LEU-PRO) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	CYCLO(-LEU-PRO) 2873-36-1	US $1.00 / kg	1kg	99%	Customized	Career Henan Chemical Co

CYCLO(-LEU-PRO)
2873-36-1
US $1.00 / kg
99%
Career Henan Chemical Co

2873-36-1(CYCLO(-LEU-PRO))Related Search:

gypsetin Pyrrolo[1,2-a]pyrazine, octahydro-3-isobutyl- (5CI) CYCLO(-GLY-PRO) (R)-HEXAHYDROPYRROLO[1,2-A]PYRAZIN-1(2H)-ONE HEXAHYDROPYRROLO[1,2-A]PYRAZINE-1,4-DIONE

(+/-)-1,4-DIAZABICYCLO[4.4.0]DECANE CYCLO(-LEU-GLY) hexahydropyrrolo[1,2-a]pyrazin-4(1H)-one VERRUCULOGEN amauromine

(S)-1,4-DIAZABICYCLO[4.3.0]NONANE 3-ISOBUTYL-6-METHYL-2,5-PIPERAZINEDIONE CYCLO(-LEU-PRO)

1of3

2-a)pyrazine-1,4-dione,hexahydro-3-isobutyl-pyrrolo(stereoisomer 4-dione,hexahydro-3-(2-methylpropyl)-2-a)pyrazine-(3s-trans)-pyrrolo( cyclo-l-leu-l-pro gancidinw (3S-trans)-hexahydro-3-isobutylpyrrolo[1,2-a]pyrazine-1,4-dione (3S,8aS)-2,3,6,7,8,8a-Hexahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione (3S,8aS)-Octahydro-3-(2-methylpropyl)pyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(L-leucyl-L-prolyl-) CYCLO(-LEU-PRO) Cyclo(L-Pro-L-Leu-) 3-(2-methylpropyl)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione 3-isobutyl-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-quinone (3S-trans)-Hexahydro-3-(2-Methylpropyl)-pyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(L-Pro-D-Leu) Cyclo(Pro-Leu) Cyclo(proline-leucine) Cyclo-L-prolyl-L-leucine L-Leucyl-L-proline lactaM L-Leucyl-L-prolyl lactaM Maculosin 6 (3S,8aS)-3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-(2-methylpropyl)-, (3S,8aS)- Cyclo(-L-Leu-L-Pro)≥ 99% (TLC) 3-Isobutylhexahydropyrrolo[1,2-a]pyrazine-1,4-dione Cyclo(L-prolyl-L-leucyl) 2873-36-1