ChemicalBook >> CAS DataBase List >>FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride structure

CAS No.: 97612-24-3

Chemical Name:: FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

Synonyms: Eticlopride HCl;Eticlopride hydrochl;S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE;(2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride;3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride;Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1);FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride

CBNumber:: CB42130556

Molecular Formula:: C17H26Cl2N2O3

Molecular Weight:: 377.31

MDL Number:: MFCD00055132

MOL File:: 97612-24-3.mol

MSDS File:: SDS

Last updated:2023-06-30 15:45:59

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FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Properties

Melting point	144-146 °C(Solv: acetone (67-64-1))
storage temp.	Desiccate at RT
solubility	H2O: soluble >10mg/mL
form	powder
color	off-white
optical activity	[α]27/D 7.2°, c = 0.3 in methanol(lit.)
Water Solubility	Soluble to 100 mM in water
FDA UNII	HJ2CAH4TZ1

SAFETY

Risk and Safety Statements

WGK Germany	3
RTECS	CV2450000

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride price More Price(8)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E101	S-(?)-Eticlopride hydrochloride ≥98% (HPLC), powder	97612-24-3	25mg	$178	2024-03-01	Buy
Sigma-Aldrich	E101	S-(?)-Eticlopride hydrochloride ≥98% (HPLC), powder	97612-24-3	100mg	$476	2024-03-01	Buy
Cayman Chemical	29112	Eticlopride (hydrochloride)	97612-24-3	5mg	$68	2024-03-01	Buy
Cayman Chemical	29112	Eticlopride (hydrochloride)	97612-24-3	10mg	$121	2024-03-01	Buy
Cayman Chemical	29112	Eticlopride (hydrochloride)	97612-24-3	25mg	$252	2024-03-01	Buy

Product number	Packaging	Price	Buy
E101	25mg	$178	Buy
E101	100mg	$476	Buy
29112	5mg	$68	Buy
29112	10mg	$121	Buy
29112	25mg	$252	Buy

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Chemical Properties,Uses,Production

Uses

Dopamine receptor antagonist

Uses

S-(?)-Eticlopride hydrochloride has been used in astrocyte-neuron coculture and functional magnetic resonance imaging (fMRI) experiments.

Biological Activity

Selective dopamine D 2 /D 3 receptor antagonist (K i values are 0.50 and 0.16 nM respectively). Antipsychotic.

Biochem/physiol Actions

Potent and selective D2 dopamine receptor antagonist. Eticlopride is highly specific for DAD2?receptors than pimozide or haloperidol. The gene encoding the D2 dopamine receptor (DRD2) is linked with a several disorders including Parkinson′s disease, schizophrenia, and susceptibility to alcoholism.

storage

room temperature (desiccate)

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride synthesis

Synthesis of FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride from 4-Ethylresorcinol dimethyl ether

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Preparation Products And Raw materials

Raw materials

Benzoic acid, 3-chloro-5-ethyl-6-hydroxy-2-methoxy- 4-Ethylresorcinol dimethyl ether (S)-2-(Aminomethyl)-1-ethylpyrrolidine

Preparation Products

FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride Suppliers

Global( 21)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8073	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
Shanghai Universal Biotech Co.,Ltd	18768175414	gaojun@univ-bio.com	China	24998	58
InvivoChem	13549236410	sales@invivochem.cn	China	6712	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Shanghai TaoSu Biochemical Technology Co., Ltd.	58
Sigma-Aldrich	80
EMMX Biotechnology LLC	60
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
MedBioPharmaceutical Technology Inc	58
Shanghai Universal Biotech Co.,Ltd	58
InvivoChem	58

97612-24-3(FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride)Related Search:

Etidronate disodium S(-)-ETICLOPRIDE HYDROCHLORIDE

S(-)-ETICLOPRIDE HYDROCHLORIDE (POTENT A ND SELECTIVE D2 DOPAMINE FLB 131, S-(-)-3-Chloro-5-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxybenzamide hydrochloride 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamidehydrochloride Eticlopride hydrochl Benzamide,3-chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-6-hydroxy-2-methoxy-,hydrochloride (1:1) (2S)-2-{[(3-chloro-5-ethyl-6-hydroxy-2-methoxybenzoyl)amino]methyl}-1-ethylpyrrolidinium chloride Eticlopride HCl 97612-24-3