5α-Hydroxy-11-methoxy-1-methyl-9,10-(methylenebisoxy)lycorenan-7-one
- CAS No.
- 1167-58-4
- Chemical Name:
- 5α-Hydroxy-11-methoxy-1-methyl-9,10-(methylenebisoxy)lycorenan-7-one
- Synonyms
- Neronine;5α-Hydroxy-11-methoxy-1-methyl-9,10-(methylenebisoxy)lycorenan-7-one;[1,3]Dioxolo[6,7][2]benzopyrano[3,4-g]indol-7(1H)-one, 2,3,5,5a,12b,12c-hexahydro-5-hydroxy-12-methoxy-1-methyl-, (5S,5aS,12bS,12cS)-
- CBNumber:
- CB42308238
- Molecular Formula:
- C18H19NO6
- Molecular Weight:
- 345.34656
- MDL Number:
- MOL File:
- 1167-58-4.mol
5α-Hydroxy-11-methoxy-1-methyl-9,10-(methylenebisoxy)lycorenan-7-one Chemical Properties,Uses,Production
Description
This alkaloid possesses a similar structure to that of Nerinine (q.v.) and is found in Nerine krigeii. It may be crystallized from AcOEt and is dextrorotatory with [0:]54 + 161.6° (c 0.57, CHC13). It is hygroscopic and behaves as a monoacidic base yielding a picrate as yellow prisms, m.p. 205-9°C (dec.); a methiodide, m.p. 260-5°C (dec.) and a crystalline O-acetate, m.p. 20t-2°C. It contains a lactone ring which may be opened by alkalies and regenerated by acids.
References
Briggs et at., J. Arner. Chern. Soc., 78,2899 (1956)
Jeffs, Hawksworth., Tetrahedron Lett., 217 (1963)
5α-Hydroxy-11-methoxy-1-methyl-9,10-(methylenebisoxy)lycorenan-7-one Preparation Products And Raw materials
Raw materials
Preparation Products
5α-Hydroxy-11-methoxy-1-methyl-9,10-(methylenebisoxy)lycorenan-7-one
Neronine
[1,3]Dioxolo[6,7][2]benzopyrano[3,4-g]indol-7(1H)-one, 2,3,5,5a,12b,12c-hexahydro-5-hydroxy-12-methoxy-1-methyl-, (5S,5aS,12bS,12cS)-
1167-58-4