ChemicalBook >> CAS DataBase List >>Pilocarpine nitrate
Pilocarpine nitrate
- CAS No.
- 148-72-1
- Chemical Name:
- Pilocarpine nitrate
- Synonyms
- Nitrat;Pilocarpine nitrate for system suitability CRS;Pilagan;pilofrin;Pilocarpinnitrat;Einecs 205-723-7;Pilocarpin Nitrate;Pilocarpini nitras;PILOCARPINE NITRATE;p.v.carpineliquifilm
- CBNumber:
- CB4237796
- Molecular Formula:
- C11H17N3O5
- Molecular Weight:
- 271.27
- MDL Number:
- MFCD00078497
- MOL File:
- 148-72-1.mol
- MSDS File:
- SDS
Last updated:2024-03-28 14:27:36
| Melting point | 173,5-174°C |
|---|---|
| alpha | D +77 to +83° (c = 10) |
| refractive index | 81 ° (C=2, H2O) |
| storage temp. | 2-8°C |
| solubility | H2O: 0.1 g/mL, clear, very faintly yellow |
| form | powder |
| color | white |
| optical activity | [α]25/D +83°, c = 10 in H2O(lit.) |
| Merck | 14,7424 |
| BRN | 4171406 |
| CAS DataBase Reference | 148-72-1(CAS DataBase Reference) |
| FDA UNII | M20T465H6J |
| EPA Substance Registry System | Pilocarpine nitrate (148-72-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS03,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H272-H302-H330 |
| Precautionary statements | P210-P220-P260-P264-P301+P312-P304+P340+P310 |
| Hazard Codes | Xn,T+ |
| Risk Statements | 22-26/28 |
| Safety Statements | 1-25-45 |
| RIDADR | 3087 |
| WGK Germany | 3 |
| RTECS | TK1455000 |
| F | 3-10 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| HS Code | 2939800000 |
| Toxicity | LD50 oral in rat: 911mg/kg |
Pilocarpine nitrate price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P0597 | Pilocarpine nitrate meets USP testing specifications | 148-72-1 | 5g | $439 | 2024-03-01 | Buy |
| Sigma-Aldrich | P0597 | Pilocarpine nitrate meets USP testing specifications | 148-72-1 | 25g | $918 | 2024-03-01 | Buy |
| Sigma-Aldrich | BP503 | Pilocarpine nitrate British Pharmacopoeia (BP) Reference Standard | 148-72-1 | 200MG | $223 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0000106 | Pilocarpine nitrate for system suitability European Pharmacopoeia (EP) Reference Standard | 148-72-1 | y0000106 | $153 | 2024-03-01 | Buy |
| Sigma-Aldrich | P6628 | Pilocarpine nitrate salt ≥98% (HPLC) | 148-72-1 | 10g | $244 | 2024-03-01 | Buy |
Pilocarpine nitrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder or colourless crystals, sensitive to light.
Uses
Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.
Uses
Antiglaucoma drug;Cholinergic
Uses
antiglaucoma agent, miotic
brand name
Pilagan (Allergan).
General Description
Pilocarpine mononitrate occursas shining white crystals that are not hygroscopic butare light sensitive. It is soluble in water (1:4) and alcohol(1:75) but insoluble in chloroform and ether. Aqueoussolutions are slightly acid to litmus and may be sterilizedin the autoclave. The alkaloid is incompatible with alkalies,iodides, silver nitrate, and reagents that precipitatealkaloids.
Biochem/physiol Actions
Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.
Pilocarpine nitrate Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 129)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 8095 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29067 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| Henan Alfa Chemical Co., Ltd | +8618339805032 | alfa4@alfachem.cn | China | 12755 | 58 |
View Lastest Price from Pilocarpine nitrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-29 | Pilocarpine nitrate
148-72-1
|
US $35.00-1.30 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2021-07-28 | Pilocarpine nitrate USP/EP/BP
148-72-1
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
-
- Pilocarpine nitrate
148-72-1
- US $35.00-1.30 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- Pilocarpine nitrate USP/EP/BP
148-72-1
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
148-72-1(Pilocarpine nitrate)Related Search:
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Pilocarpine NitrateQ: What is
Pilocarpine Nitrate Q: What is the CAS Number of
Pilocarpine Nitrate Q: What is the storage condition of
Pilocarpine Nitrate Q: What are the applications of
Pilocarpine Nitrate
Pilocarpine nitrate USP/EP/BP
Pilocarpine nitrate CRS
Pilocarpine Nitrate Impurity Ⅰ:(3R,4R)-3-ethyl-4-((1-Methyl-1H-iMidazol-5-yl)Methyl)dihydrofuran-2(3H)-one nitrate
Pilocarpine nitrate for system suitability CRS
Nitrat
Pilocarpinenitratesal
Pilocarpine,Inhibitor,inhibit,mAChR,Muscarinic acetylcholine receptor,Pilocarpine nitrate
(2R,3R)-2-ethyl-3-(hydroxymethyl)-4-(1-methyl-1H-imidazol-5-yl)butanoic acid (isopilocarpic acid)
Ametryn Impurity 21(Simetryne)
148-72-1
C11H16N2O2HNO3
Alkaloids (Others)
Alkaloids
Inhibitors
AgonistsDrugs of Abuse
Chemical Structure
Cholinergics
Neurotransmitters
Others
Alkaloids
Alkaloids (Others)
Biochemistry
API