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EUK 124

EUK 124 Structure
EUK 124 structure
CAS No.
186299-35-4
Chemical Name:
EUK 124
Synonyms
EUK 124;VCQQGEFBIFYGQL-AIMLMLFYSA-K
CBNumber:
CB42456379
Molecular Formula:
C20H22ClMnN2O6
Molecular Weight:
476.79
MDL Number:
MFCD11113151
MOL File:
186299-35-4.mol
Last updated:2023-04-23 13:52:06
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EUK 124 Properties

solubility DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form A crystalline solid

EUK 124 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 12500 EUK 124 ≥95% 186299-35-4 5mg $39 2024-03-01 Buy
Cayman Chemical 12500 EUK 124 ≥95% 186299-35-4 10mg $73 2024-03-01 Buy
Usbiological 167822 EUK-124 186299-35-4 5mg $270 2021-12-16 Buy
ApexBio Technology C4679 EUK124 186299-35-4 10mg $82 2021-12-16 Buy
AK Scientific 1672AH Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-kappan)methylidyne]]bis[3,5-dimethoxyphenolato-kappao]](2-)]-manganese 186299-35-4 5mg $141 2021-12-16 Buy
Product number Packaging Price Buy
12500 5mg $39 Buy
12500 10mg $73 Buy
167822 5mg $270 Buy
C4679 10mg $82 Buy
1672AH 5mg $141 Buy

EUK 124 Chemical Properties,Uses,Production

Description

EUK 8 and EUK 134 are synthetic catalytic scavengers of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity.1 EUK 124 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity. EUK 124 and EUK 8 inhibit superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity), with IC50 values of 5 μM and 0.7 μM, respectively.2

References

1. Baker, K., Marcus, C.B., Huffman, K., et al. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury J. Pharmacol. Exp. Ther. 284(1),215-221(1998).
2. Doctrow, S.R., Huffman, K., Marcus, C.B., et al. Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: Structure-activity relationship studies J. Med. Chem. 45,4549-4558(2002).

EUK 124 Preparation Products And Raw materials

Raw materials

Preparation Products

EUK 124 Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8740 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 market@aladdin-e.com China 48467 58
ApexBio Technology -- sales@apexbt.com United States 6254 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Aladdin Scientific 		58
MedBioPharmaceutical Technology Inc 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
ApexBio Technology 58

186299-35-4(EUK 124)Related Search:

N,N'-BIS(SALICYLIDENE)ETHYLENEDIAMINE EUK 124
EUK 124 VCQQGEFBIFYGQL-AIMLMLFYSA-K 186299-35-4 C20H22ClMnN2O6