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ChemicalBook >> CAS DataBase List >>(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester

(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester

(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester Structure
(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester structure
CAS No.
543906-09-8
Chemical Name:
(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester
Synonyms
AFQ 056;GT0I9SV4F6;Mavoglurant;SureCN989279;CHEMBL3087515;UNII-GT0I9SV4F6;Mavoglurant, AFQ056;(3aR,4S,7aR)-Methyl 4-hydroxy-4-(2-M-tolylethynyl)-octahydroindole-1-carboxylate;methyl (3aR,4S,7aR)-4-hydroxy-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate;UNII-GT0I9SV4F6; AFQ056; MAVOGLURANT; SURECN989279; GT0I9SV4F6; CHEMBL3087515; AFQ 056; AFQ-056
CBNumber:
CB42510066
Molecular Formula:
C19H23NO3
Molecular Weight:
313.39
MDL Number:
MOL File:
543906-09-8.mol
MSDS File:
SDS
Last updated:2023-05-18 11:31:06
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(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester Properties

Melting point 119 - 121°C
Boiling point 476.3±45.0 °C(Predicted)
Density 1.21
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 12.75±0.20(Predicted)
form Solid
color White to Off-White
FDA UNII GT0I9SV4F6

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M197920 Mavoglurant 543906-09-8 10mg $445 2021-12-16 Buy
ChemScene CS-5245 Mavoglurant 99.99% 543906-09-8 10mg $540 2021-12-16 Buy
ChemScene CS-5245 Mavoglurant 99.99% 543906-09-8 5mg $420 2021-12-16 Buy
ChemScene CS-5245 Mavoglurant 99.99% 543906-09-8 50mg $1800 2021-12-16 Buy
ChemScene CS-5245 Mavoglurant 99.99% 543906-09-8 100mg $2520 2021-12-16 Buy
Product number Packaging Price Buy
M197920 10mg $445 Buy
CS-5245 10mg $540 Buy
CS-5245 5mg $420 Buy
CS-5245 50mg $1800 Buy
CS-5245 100mg $2520 Buy

(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester Chemical Properties,Uses,Production

Uses

Mavoglurant is a non-competitive metabotropic glutamate receptor 5 (mGlu5) receptor antagonist.

(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626 eric@witopchemical.com China 23556 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501 product@acmec-e.com China 33350 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131980 58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 17702719238 17702719238 sales@sun-shinechem.com China 918 64
Tianjin Derchemist Science & Technology Co., Ltd. 22-58627059 13920586291 zdcomcon@126.com China 3021 50
Haoyuan Chemexpress Co., Ltd. 021-58950125 info@chemexpress.com China 7553 61
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4863 58
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8015 62
Supplier Advantage
TargetMol Chemicals Inc. 		58
ANHUI WITOP BIOTECH CO., LTD 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Amadis Chemical Company Limited 		58
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. 64
Tianjin Derchemist Science & Technology Co., Ltd. 50
Haoyuan Chemexpress Co., Ltd. 61
MedChemexpress LLC 58
ShangHai Biochempartner Co.,Ltd 62
(3aR,4S,7aR)-Octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1H-indole-1-carboxylic acid methyl ester (3aR,4S,7aR)-Methyl 4-hydroxy-4-(2-M-tolylethynyl)-octahydroindole-1-carboxylate Mavoglurant AFQ 056 Mavoglurant, AFQ056 UNII-GT0I9SV4F6; AFQ056; MAVOGLURANT; SURECN989279; GT0I9SV4F6; CHEMBL3087515; AFQ 056; AFQ-056 CHEMBL3087515 GT0I9SV4F6 SureCN989279 UNII-GT0I9SV4F6 1H-Indole-1-carboxylic acid, octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-, methyl ester, (3aR,4S,7aR)- methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-3,3a,5,6,7,7a-hexahydro-2H-indole-1-carboxylate methyl (3aR,4S,7aR)-4-hydroxy-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate 543906-09-8