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ChemicalBook >> CAS DataBase List >>(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Structure
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one structure
CAS No.
870281-86-0
Chemical Name:
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
Synonyms
CAL10;CAL-101(N-1);Idelalisib INT;IdelalisibIntermediates 1;CAL-101 (N-1) Intermediate;(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one;2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone;4(3H)-Quinazolinone, 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-;2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one;(S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
CBNumber:
CB42623630
Molecular Formula:
C17H16FN3O
Molecular Weight:
297.33
MDL Number:
MFCD22124614
MOL File:
870281-86-0.mol
MSDS File:
SDS
Last updated:2023-05-15 10:44:01
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(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Properties

Boiling point 455.3±55.0 °C(Predicted)
Density 1.27±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Chloroform (Slightly), DMSO (Slightly), Ethanol (Sparingly)
form Solid
pka 8.23±0.29(Predicted)
color Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A628755 2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone 870281-86-0 1g $180 2021-12-16 Buy
TRC A628755 2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone 870281-86-0 2.5g $275 2021-12-16 Buy
AK Scientific 2965AH (S)-2-(1-Aminopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 870281-86-0 1g $323 2021-12-16 Buy
Biosynth Carbosynth FA96431 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone 870281-86-0 5G $220 2021-12-16 Buy
Biosynth Carbosynth FA96431 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone 870281-86-0 10g $270 2021-12-16 Buy
Product number Packaging Price Buy
A628755 1g $180 Buy
A628755 2.5g $275 Buy
2965AH 1g $323 Buy
FA96431 5G $220 Buy
FA96431 10g $270 Buy

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Chemical Properties,Uses,Production

Uses

2-[(1S)-1-Aminoprpyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone is used as reagent/reactant in synthetic preparation of idelalisib using the HMDS/I2-catalyzed cyclocondensation and Boc deprotection of an (aminobutyrylamino)benzamide to a nonracemic quinazoline as the key step.

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one synthesis

870281-85-9
870281-86-0
Synthesis of (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one from (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Preparation Products And Raw materials

Raw materials

(S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate

Preparation Products

CAL-101

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one Suppliers

Global( 111)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Rokechem Technology Co., Ltd.
18758118018 sales001@rokechem.com China 255 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15932 58
Fluoropharm Co., Ltd. 		+86-0571-85586753; +8613336034509 sales@fluoropharm.com China 1377 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Lianyungang happen teng technology co., LTD 		15950718863 wang666xt@163.com CHINA 295 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Biochempartner 		0086-13720134139 candy@biochempartner.com CHINA 967 58
Chongqing Chemdad Co., Ltd 		+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
Supplier Advantage
Changzhou Rokechem Technology Co., Ltd.
58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Fluoropharm Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Lianyungang happen teng technology co., LTD 		58
career henan chemical co 		58
Biochempartner 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58

View Lastest Price from (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one pictures 2022-10-01 (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
870281-86-0
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one pictures 2022-08-16 (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
870281-86-0
 US $0.00 / kg 1kg 99%min 1-50kg Changzhou Rokechem Technology Co., Ltd.
(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one pictures 2019-07-06 (S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
870281-86-0
 US $1.00 / KG 1KG 98% 100KG Career Henan Chemical Co

870281-86-0((S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one)Related Search:

Idelalisib Impurity 8 2-aMino-6-fluoro-N-phenylbenzaMide hydrochloride 2-Amino-6-fluorobenzoic acid BOC-ABU-OH (S)-tert-butyl (1-(5-fluoro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)propyl)carbaMate
CAL-101 2-Fluoro-6-nitro-N-phenylbenzamide

1of2

(S)-2-(1-aMinopropyl)-5-fluoro-3-phenylquinazolin-4(3H)-one 2-[(1S)-1-Aminopropyl]-5-fluoro-3-phenyl-4(3H)-quinazolinone Idelalisib INT CAL-101 (N-1) Intermediate (S)-2-(1-((9H-purin-6-yl-2,8-d2)amino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one CAL10 IdelalisibIntermediates 1 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl-3,4-dihydroquinazolin-4-one CAL-101(N-1) 4(3H)-Quinazolinone, 2-[(1S)-1-aminopropyl]-5-fluoro-3-phenyl- 870281-86-0 intermediate intermediates