ChemicalBook >> CAS DataBase List >>CPI 360
CPI 360
- CAS No.
- 1802175-06-9
- Chemical Name:
- CPI 360
- Synonyms
- CPI360;CPI-360;CPI 360;CPI-360 (R);CPI360;CPI 360;1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-
- CBNumber:
- CB42729358
- Molecular Formula:
- C25H31N3O4
- Molecular Weight:
- 437.53
- MDL Number:
- MFCD28167834
- MOL File:
- 1802175-06-9.mol
Last updated:2024-04-18 17:30:06
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| NFPA 704 |
|
CPI 360 price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 19125 | CPI-360 ≥98% | 1802175-06-9 | 500μg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 19125 | CPI-360 ≥98% | 1802175-06-9 | 1mg | $68 | 2024-03-01 | Buy |
| Cayman Chemical | 19125 | CPI-360 ≥98% | 1802175-06-9 | 5mg | $231 | 2024-03-01 | Buy |
| Cayman Chemical | 19125 | CPI-360 ≥98% | 1802175-06-9 | 10mg | $424 | 2024-03-01 | Buy |
| AK Scientific | 6715DW | CID73442743 | 1802175-06-9 | 10mg | $569 | 2021-12-16 | Buy |
CPI 360 Chemical Properties,Uses,Production
Description
CPI-360 is a selective EZH2 inhibitor with IC50 values of 0.5 and 2.5 nM for wild-type EZH2 and Y641N mutant EZH2, respectively. It decreases cellular levels of H3K27me3 and H3K27me2 (EC50s = 56 and 65 nM, respectively), triggering cell cycle arrest and ultimately resulting in apoptosis in a large panel of non-Hodgkin’s lymphoma (NHL) cell lines. Twice daily, subcutaneous administration of 200 mg/kg of CPI-360 reduced tumor growth of KARPAS-422 xenografts in mice.
CPI 360 Preparation Products And Raw materials
Raw materials
Preparation Products
CPI 360 Suppliers
Global( 80)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Chuchang Biotech Co., Ltd. | +86-18727130788 +86-18727130788 | info@chuchangbiotech.com | China | 100 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 2698 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Zhengzhou convergence chemical co., LTD | 0371-0371-55153829 18003835034 | 2853979819@qq.com | China | 8701 | 58 |
| Hubei Chuchang Chemical Co., Ltd | 15623560702 | Joy.Ren@aliyun.com | China | 139 | 58 |
View Lastest Price from CPI 360 manufacturers
CPI 360
CPI360
CPI-360
CPI360;CPI 360
CPI-360 (R)
1H-Indole-3-carboxamide, N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-
1802175-06-9