BEAUVERICIN
- CAS No.
- 26048-05-5
- Chemical Name:
- BEAUVERICIN
- Synonyms
- nivea;bovein;bassiana;beauverin;Beauveria;BEAUVERICIN;BEAUVERFICIN;Beauveria sp.;Beauvericin 97%;13C45-Beauvericin
- CBNumber:
- CB4345714
- Molecular Formula:
- C45H57N3O9
- Molecular Weight:
- 783.95
- MDL Number:
- MFCD30541349
- MOL File:
- 26048-05-5.mol
| Melting point | 93-94℃ |
|---|---|
| Boiling point | 975.6±65.0 °C(Predicted) |
| Density | 1.126±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO (30 mg/ml) |
| pka | -1.02±0.70(Predicted) |
| color | White |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| InChIKey | GYSCAQFHASJXRS-ABKJGVMTSA-N |
| EWG's Food Scores | 1 |
| FDA UNII | 26S048LS2R |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H319-H335-H315-H302+H312+H332 |
| Precautionary statements | P280-P261-P271 |
| WGK Germany | 3 |
| HS Code | 29419090 |
BEAUVERICIN price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B7510 | Beauvericin ≥97% (HPLC) | 26048-05-5 | 5mg | $218 | 2024-03-01 | Buy |
| Sigma-Aldrich | 37012 | Beauvericin VETRANAL?, analytical standard | 26048-05-5 | 100μg | $895 | 2022-05-15 | Buy |
| Cayman Chemical | 11426 | Beauvericin ≥95% | 26048-05-5 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 11426 | Beauvericin ≥95% | 26048-05-5 | 5mg | $139 | 2024-03-01 | Buy |
| Cayman Chemical | 11426 | Beauvericin ≥95% | 26048-05-5 | 10mg | $261 | 2024-03-01 | Buy |
BEAUVERICIN Chemical Properties,Uses,Production
Description
Beauvericin (CAS 26048-05-5) induces apoptosis in A549 cancer cells.1 Disrupts mitochondrial volume regulation.2 Antifungal activity acting via inhibition of both multidrug efflux and TORC1 kinase.3 Crosses the blood-brain barrier in mice.4 Inhibits HIV-1 integrase.5
Chemical Properties
White powder
Uses
Toxic depsipeptide with antibiotic and insecticidal effects.Beauvericin is a toxic depsipeptide with antibiotic and insecticidal effects.
Uses
Beauvericin is a cyclic depsipeptide isolated from several fungal genera, notably Beauveria and Fusarium, first reported in 1969. Beauvericin exhibits broad antifungal, antibacterial, antiprotozoan and insecticidal activities. At the molecular level, beauvericin exhibits ionophoric properties, and inhibits acyl-CoA:cholesterol acyltransferase activity. Beauvericin induces apoptosis by elevating intracellular calcium levels.
Definition
ChEBI: A trimeric cyclodepsipeptide composed from alternating methylphenylalanyl and hydroxyvaleryl residues.
References
1) Lu et al. (2016), Beauvericin-induced cell apoptosis through the mitogen-activated protein kinase pathway in human nonsmall cell lung cancer A549 cells.; J. Toxicol. Sci., 41 429 2) Tonshin et al. (2010), The Fusarium mycotoxins enniatins and beauvericin cause mitochondrial dysfunction by affecting the mitochondrial volume regulation, oxidative phosphorylation and ion homeostasis.; Toxicology, 276 49 3) Shekhar-Guturja et al. (2016), Dual action antifungal small molecule modulates multidrug efflux and TOR signaling; Nat. Chem. Biol., 12 867 4) Taevernier et al. (2016), Blood-brain barrier transport kinetics of the cyclic depsipeptide mycotoxins beauvericin and enniatins; Toxicol. Lett., 258 175 5) Shin et al. (2009), Beauvericin and enniatins H,I and MK1688 are new potent inhibitors of human immunodeficiency virus type-1 integrase; J. Antibiot. (Tokyo), 62 687
BEAUVERICIN Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 476 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
View Lastest Price from BEAUVERICIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | BEAUVERICIN
26048-05-5
|
US $20.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd | |
 |
2022-05-18 | Beauvericin
26048-05-5
|
US $0.00 / g | 10g | 99.0% | 10tons | Wuhan Godbullraw Chemical Co.,ltd | |
 |
2022-05-11 | Beauvericin
26048-05-5
|
US $0.00 / KG | 0.01KG | 99% | 1 tons | Wuhan Godbullraw Chemical Co.,ltd |
-
- BEAUVERICIN
26048-05-5
- US $20.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
-
- Beauvericin
26048-05-5
- US $0.00 / g
- 99.0%
- Wuhan Godbullraw Chemical Co.,ltd
-
- Beauvericin
26048-05-5
- US $0.00 / KG
- 99%
- Wuhan Godbullraw Chemical Co.,ltd
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