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BAY-598 R-isomer

BAY-598 R-isomer structure

CAS No.: 1906920-28-2

Chemical Name:: BAY-598 R-isomer

Synonyms: (R)-BAY-598;BAY-598 R-isomer;BAY598 Risomer,BAY 598 R isomer;N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-acetamide;Acetamide, N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-

CBNumber:: CB44920777

Molecular Formula:: C22H20Cl2F2N6O3

Molecular Weight:: 525.34

MDL Number:

MOL File:: 1906920-28-2.mol

Last updated:2023-05-21 10:59:17

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BAY-598 R-isomer Properties

Boiling point	663.5±65.0 °C(Predicted)
Density	1.46±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: soluble
form	A solid
pka	13.34±0.10(Predicted)

BAY-598 R-isomer price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	29174	(R)-BAY-598	1906920-28-2	1mg	$65	2024-03-01	Buy
Cayman Chemical	29174	(R)-BAY-598	1906920-28-2	10mg	$494	2024-03-01	Buy
Cayman Chemical	29174	(R)-BAY-598	1906920-28-2	500μg	$37	2024-03-01	Buy
Cayman Chemical	29174	(R)-BAY-598	1906920-28-2	5mg	$266	2024-03-01	Buy

Product number	Packaging	Price	Buy
29174	1mg	$65	Buy
29174	10mg	$494	Buy
29174	500μg	$37	Buy
29174	5mg	$266	Buy

BAY-598 R-isomer Chemical Properties,Uses,Production

Description

BAY-598 R-isomer is the R-isomer of BAY589. BAY-598 R-isomer may be used as a reference compound. BAY-598 is a potent, peptide-competitive chemical probe for SMYD2. BAY-598 has a unique chemotype relative to the current SMYD2 chemical probe LLY-507. BAY-598 inhibits in vitro methylation of p53K370 with IC50 = 27 nM and has more than 100-fold selectivity over other histone methyltransferases and other non-epigenetic targets. BAY-598 inhibits the methylation of p53K370 in cells with IC50 < 1 μM. (Further to this, BAY-598 has properties that are compatible with in vivo experiments.) A control compound, BAY-369, has also been developed. BAY-369 inhibits the in vitro methylation of p53K370 with IC50 > 70 micromolar.

BAY-598 R-isomer Preparation Products And Raw materials

Raw materials

Preparation Products

BAY-598 R-isomer Suppliers

Global( 11)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
InvivoChem	13549236410	sales@invivochem.cn	China	6713	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24018	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	5143	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
InvivoChem	58
Shanghai Hongye Biotechnology Co. Ltd	58
BOC Sciences	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Changzhou Furuisi Biotechnology Co., Ltd	58
InvivoChem	58
TargetMol Chemicals Inc.	58
Nanjing Tengyi Biotechnology Co., Ltd	58
Shanghai Yifei Biotechnology Co. , Ltd.	58

BAY-598 R-isomer (R)-BAY-598 BAY598 Risomer,BAY 598 R isomer Acetamide, N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy- N-[(4R)-1-[(cyanoamino)[[3-(difluoromethoxy)phenyl]imino]methyl]-3-(3,4-dichlorophenyl)-4,5-dihydro-1H-pyrazol-4-yl]-N-ethyl-2-hydroxy-acetamide 1906920-28-2