Ozagrel hydrochloride
- CAS No.
- 78712-43-3
- Chemical Name:
- Ozagrel hydrochloride
- Synonyms
- Vega;Ozag;Domenan;OKY-046 HCl;(e)-ohydrat;OZAGREL HCL;OzagrelHcl99%;oky046hydrochloride;Ozagrel Impurity 44;oky-046hydrochloride
- CBNumber:
- CB4765488
- Molecular Formula:
- C13H13ClN2O2
- Molecular Weight:
- 264.71
- MDL Number:
- MFCD00911569
- MOL File:
- 78712-43-3.mol
| Melting point | 214-217° |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | H2O: soluble |
| form | solid |
| color | white to off-white |
| Merck | 14,6980 |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in distilled water may be stored at -20° for up to 1 month. |
| CAS DataBase Reference | 78712-43-3(CAS DataBase Reference) |
| FDA UNII | W222U960HS |
Ozagrel hydrochloride price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | O1385 | Ozagrel hydrochloride hydrate ≥98% (HPLC), solid | 78712-43-3 | 5mg | $132 | 2024-03-01 | Buy |
| Sigma-Aldrich | O1385 | Ozagrel hydrochloride hydrate ≥98% (HPLC), solid | 78712-43-3 | 25mg | $354 | 2022-05-15 | Buy |
| TCI Chemical | O0419 | Ozagrel Hydrochloride Hydrate >98.0%(HPLC)(T) | 78712-43-3 | 1g | $42 | 2024-03-01 | Buy |
| TCI Chemical | O0419 | Ozagrel Hydrochloride Hydrate >98.0%(HPLC)(T) | 78712-43-3 | 5g | $124 | 2024-03-01 | Buy |
| Tocris | 1510 | Ozagrelhydrochloride ≥98%(HPLC) | 78712-43-3 | 50 | $437 | 2021-12-16 | Buy |
Ozagrel hydrochloride Chemical Properties,Uses,Production
Description
Ozagrel HCl (78712-43-3) is a potent and selective inhibitor of thromboxane (TXA2) synthetase (IC50 = 4 nM).1?Does not inhibit prostacyclin (PGI2) synthase, cyclooxygenase or PGE2?isomerase (IC50 > 1 mM).1?Inhibits platelet aggregation2?in vitro?and arachidonate-induced arterial contraction?in vivo. Ozagrel HCl protects against arachidonate-induced sudden death in the rabbit3, and alleviates liver injury induced by acetaminophen overdose in mice4.
Uses
Ozagrel Hydrochloride is a selective thromboxane A2 synthase inhibitor, which alleviates liver injury induced by acetaminophen overdose in mice.
Uses
Antithrombotic;Thromboxane synthase inhibitor
Definition
ChEBI: Ozagrel hydrochloride is an organic molecular entity.
References
1) Hiraku?et al. (1986),?Pharmacological studies on the TXA2?synthetase inhibitor (E)-3-[p-(1H-imidazol-1-ylmethyl)phenyl]-2-propenoic acid (OKY-046); Jpn. J. Pharmacol.,?41?393 2) Naito?et al. (1983), Effects of thromboxane synthetase inhibitors on aggregation of rabbit platelets; Eur. J. Pharmacol.,?91?41 3) Edmonds and Leffer (1984),?Protective actions of a new thromboxane synthetase inhibitor in arachidonate induced sudden death; Life Sci.,?35?1763 4) Tomishima?et al. (2013),?Ozagrel hydrochloride, a selective thromboxane A2?synthase inhibitor, alleviates liver injury induced by acetaminophen overdose in mice; BMC Gastroenterol.,?30?13
Ozagrel hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 | faith@widelychemical.com | CHINA | 742 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
| Hebei Lingding Biotechnology Co., Ltd. | +86-18031140164 +86-19933155420 | erin@hbldbiotech.com | China | 878 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29220 | 58 |
| AFINE CHEMICALS LIMITED | 0571-85134551 | info@afinechem.com | CHINA | 15377 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 | 2571773637@qq.com | China | 9821 | 58 |
View Lastest Price from Ozagrel hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-10-20 | Ozagrel hydrochloride
78712-43-3
|
US $30.00 / KG | 1KG | 99% | 9000kg/per week | Hebei Lingding Biotechnology Co., Ltd. | |
 |
2021-07-02 | Ozagrel hydrochloride
78712-43-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | Ozagrel hydrochloride
78712-43-3
|
US $1.00 / kg | 1kg | 99% | Customized | Career Henan Chemical Co |
-
- Ozagrel hydrochloride
78712-43-3
- US $30.00 / KG
- 99%
- Hebei Lingding Biotechnology Co., Ltd.
-
- Ozagrel hydrochloride
78712-43-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Ozagrel hydrochloride
78712-43-3
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
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