Phthalimidine, 2-(2,6-dioxopiperiden-3-yl).
- CAS No.
- 26581-81-7
- Chemical Name:
- Phthalimidine, 2-(2,6-dioxopiperiden-3-yl).
- Synonyms
- EM12;CID91585;Thalidomide Impurity 4;PHTHALIMIDINOGLUTARIMIDE;2-(1-Oxo-2-isoindolinyl)glutarimide;2-(2,6-dioxopiperidin-3-yl)phthalimidine;2-(2,6-Dioxopiperiden-3-yl) phthalimidine;Phthalimidine, 2-(2,6-dioxopiperiden-3-yl).;2-(2,6-Dioxo-3-piperidinyl)isoindoline-1-one;3-(1-Oxoisoindolin-2-yl)-2,6-piperidinedione
- CBNumber:
- CB51251808
- Molecular Formula:
- C13H12N2O3
- Molecular Weight:
- 244.25
- MDL Number:
- MOL File:
- 26581-81-7.mol
| Boiling point | 383.99°C (rough estimate) |
|---|---|
| Density | 1.2650 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | -20°C |
| solubility | DMF: 5 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 1 mg/ml |
| form | A crystalline solid |
| pka | 10.70±0.40(Predicted) |
| EPA Substance Registry System | 2-(1-Oxo-2-isoindolinyl)glutarimide (26581-81-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H335-H319-H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362 | |||||||||
| NFPA 704 |
|
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | CHM0968938 | PHTHALIMIDINE, 2-(2,6-DIOXOPIPERIDEN-3-YL) 95.00% | 26581-81-7 | 5MG | $500.89 | 2021-12-16 | Buy |
| AK Scientific | 6304CA | 3-(1,3-Dihydro-1-oxo-2h-isoindol-2-yl)-2,6-piperidinedione | 26581-81-7 | 5g | $3956 | 2021-12-16 | Buy |
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). Chemical Properties,Uses,Production
Description
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl) is a lenalidomide analog that can be useful in PROTAC research.
General Description
White crystalline powder.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). is an example of an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Health Hazard
ACUTE/CHRONIC HAZARDS: When heated to decomposition Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). emits toxic fumes of nitrogen oxides.
Fire Hazard
Flash point data for Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). are not available; however, Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). is probably combustible.
Phthalimidine, 2-(2,6-dioxopiperiden-3-yl). Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| China National Standard Pharmaceutical Corporation Limited | +8615391658522 | overseasales@yongstandards.com | China | 11927 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 6000 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-4000505016 13380397412 | 3001272453@qq.com | China | 4975 | 50 |
| Shanghai Kewel Chemical Co., Ltd. | 021-64609169 18901607656 | greensnown@163.com | China | 9911 | 50 |
| ATK CHEMICAL COMPANY LIMITED | 3429815786 13301662590 | sales@atkchemical.com | China | 10006 | 55 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9445 | 58 |
| Amatek Scientific Co. Ltd. | 0512-56316828 | info@amateksci.com | China | 28822 | 58 |