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2-COUMARANONE

2-COUMARANONE Structure
2-COUMARANONE structure
CAS No.
553-86-6
Chemical Name:
2-COUMARANONE
Synonyms
BENZOFURANONE;2-Cumaranon;2-Coumaronone;2-COUMARANONE;ISOCOUMARANONE;2H-BENZOFURANONE;BENZOFURAN-2-ONE;2-Coumaranone,99%;2-Coumaranone,97%;2-Coumaranone 97%
CBNumber:
CB5131550
Molecular Formula:
C8H6O2
Molecular Weight:
134.13
MDL Number:
MFCD00005856
MOL File:
553-86-6.mol
MSDS File:
SDS
Last updated:2024-04-10 11:19:08
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2-COUMARANONE Properties

Melting point 49-51 °C(lit.)
Boiling point 248-250 °C(lit.)
Density 1,22 g/cm3
vapor pressure 0.027-0.24Pa at 10-30℃
refractive index 1.4800 (estimate)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility H2O: soluble3.8g/L at 30°C
form Crystalline Powder or Crystals
color White to yellow-orange
BRN 114689
InChIKey ACZGCWSMSTYWDQ-UHFFFAOYSA-N
LogP 1.347
Surface tension 63.8mN/m at 1g/L and 20℃
CAS DataBase Reference 553-86-6(CAS DataBase Reference)
FDA UNII 4K47Z4Q1E7

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H317-H319
Precautionary statements  P280-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-36/37/38-43-36/38
Safety Statements  24/25-36-26-36/37
WGK Germany  3
HS Code  29322090
NFPA 704
1
2 0

2-COUMARANONE price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 124591 2-Coumaranone 97% 553-86-6 1g $46 2024-03-01 Buy
Sigma-Aldrich 124591 2-Coumaranone 97% 553-86-6 10g $199 2024-03-01 Buy
TCI Chemical C1445 2-Coumaranone >98.0%(GC) 553-86-6 5g $64 2024-03-01 Buy
TCI Chemical C1445 2-Coumaranone >98.0%(GC) 553-86-6 25g $185 2024-03-01 Buy
Alfa Aesar A18617 2-Coumaranone, 99% 553-86-6 1g $39.65 2024-03-01 Buy
Product number Packaging Price Buy
124591 1g $46 Buy
124591 10g $199 Buy
C1445 5g $64 Buy
C1445 25g $185 Buy
A18617 1g $39.65 Buy

2-COUMARANONE Chemical Properties,Uses,Production

Description

2-Coumaranone (also named as Isophthalide, 3H-benzofuran-2-one) belongs to a class of organic compounds named as benzofuranones which exhibits mutagenic and carcinogenic activity. 2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland and as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures.

Reference

Y. S. Priya, K. Ramachandra Rao, P. V. Chalapathi, M. Satyavani, A. Veeraiah, Vibrational and UV spectroscopic studies of 2-coumaranone by experimental and density functional theory calculations, Journal of Molecular Structure, 2017, vol. 1144, pp. 535-544

Chemical Properties

WHITE TO LIGHT YELLOW CRYSTALLINE POWDER

Uses

2-Coumaranone has been used to study the effects of coumarins on 7,12-dimethyibenz(a)anthracene induced neoplasia of the rat mammary gland. It was employed as probe for detecting enzymes which hydrolyze 2-hydroxybenzofuran structures.

Synthesis Reference(s)

The Journal of Organic Chemistry, 47, p. 2491, 1982 DOI: 10.1021/jo00133a055

2-COUMARANONE synthesis

614-75-5
553-86-6
Synthesis of 2-COUMARANONE from 2-Hydroxyphenylacetic acid

2-COUMARANONE Preparation Products And Raw materials

Raw materials

Preparation Products

2(3H)-Benzofuranone, 3-(hydroxymethylene)-

2-COUMARANONE Suppliers

Global( 327)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Benoy Chemical Co., Ltd
+8617342059697 sales@benoychem.com China 315 58
airuikechemical co., ltd. 		+undefined86-15315557071 sales02@airuikechemical.com China 994 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Dalian Richfortune Chemicals Co., Ltd 		0411-84820922 8613904096939 sales@richfortunechem.com China 303 57
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28180 58
Jinan Finer Chemical Co., Ltd 		+86-531-88989536 +86-15508631887 sales@finerchem.com China 2967 58
Accela ChemBio Inc. 		(+1)-858-699-3322 info@accelachem.com United States 19965 58
Supplier Advantage
Hangzhou Benoy Chemical Co., Ltd
58
airuikechemical co., ltd. 		58
Capot Chemical Co.,Ltd. 		60
Dalian Richfortune Chemicals Co., Ltd 		57
Henan Tianfu Chemical Co.,Ltd. 		55
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Hubei Jusheng Technology Co.,Ltd. 		58
Jinan Finer Chemical Co., Ltd 		58
Accela ChemBio Inc. 		58

View Lastest Price from 2-COUMARANONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-COUMARANONE pictures 2024-04-10 2-COUMARANONE
553-86-6
 US $0.00-0.00 / g 1g 99.99% 20 tons airuikechemical co., ltd.
2-COUMARANONE pictures 2023-03-22 2-COUMARANONE
553-86-6
 US $1.00 / kg 1kg 99.8% 20tons Hebei Duling International Trade Co. LTD
2-Coumaranone pictures 2023-03-18 2-Coumaranone
553-86-6
 US $5.00-2.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
  • 2-COUMARANONE pictures
  • 2-COUMARANONE
    553-86-6
  • US $0.00-0.00 / g
  • 99.99%
  • airuikechemical co., ltd.
  • 2-COUMARANONE pictures
  • 2-COUMARANONE
    553-86-6
  • US $1.00 / kg
  • 99.8%
  • Hebei Duling International Trade Co. LTD
  • 2-Coumaranone pictures
  • 2-Coumaranone
    553-86-6
  • US $5.00-2.00 / KG
  • 99%
  • Hebei Guanlang Biotechnology Co,.LTD

2-COUMARANONE Spectrum

2-COUMARANONE(553-86-6)MS2-COUMARANONE(553-86-6)1HNMR2-COUMARANONE(553-86-6)13CNMR2-COUMARANONE(553-86-6)IR12-COUMARANONE(553-86-6)IR22-COUMARANONE(553-86-6)Raman

553-86-6(2-COUMARANONE)Related Search:

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