3-O-trans-p-CouMaroyltorMentic acid
- CAS No.
- 121064-78-6
- Chemical Name:
- 3-O-trans-p-CouMaroyltorMentic acid
- Synonyms
- 3-O-p-CouMaroyltorMentic acid;3-O-trans-p-Coumaroyltormenticaci;3-O-trans-p-CouMaroyltorMentic acid;Urs-12-en-28-oic acid, 2,19-dihydroxy-3-[[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]oxy]-, (2α,3β)-
- CBNumber:
- CB52566525
- Molecular Formula:
- C39H54O7
- Molecular Weight:
- 634.85
- MDL Number:
- MFCD28100311
- MOL File:
- 121064-78-6.mol
- MSDS File:
- SDS
3-O-trans-p-CouMaroyltorMentic acid price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| American Custom Chemicals Corporation | PXT0003546 | 3-O-TRANS-PARA-COUMAROYLTORMENTIC ACID 95.00% | 121064-78-6 | 5MG | $495.58 | 2021-12-16 | Buy |
| Arctom | CFN97843 | 3-O-trans-p-Coumaroyltormenticacid ≥98% | 121064-78-6 | 5mg | $593 | 2021-12-16 | Buy |
| Crysdot | CD32002705 | 3-O-p-Coumaroyltormenticacid 95+% | 121064-78-6 | 5mg | $922 | 2021-12-16 | Buy |
3-O-trans-p-CouMaroyltorMentic acid Chemical Properties,Uses,Production
Description
3-O-(E)-p-coumaroyl tormentic acid induces apoptotic cell death in human leukemia (HL60) via mainly mitochondrial pathway by, at least in part, Topo I inhibition, it may be promising lead compound for developing an effective drug for treatment of leukemia. 3-O-trans-p-coumaroyltormentic acid shows cytotoxicity against four human tumor cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-15) in vitro, the IC50 values of 13.72, 14.29,14.61, 14.04 uM, respectively. 3. 3beta-O-cis-p-Coumaroyltormentic acid, and 3beta-O-trans-p-coumaroyltormentic acid are weakly selective for vancomycin-resistant Enterococcus (VRE) compared with eukaryotic cells, with an MIC of 59.4microg/mL and a 50% inhibitory concentration (IC50) of 70microg/mL for monkey kidney epithelial (MA104) cells. 4. A mixture of 3-O-cis-p-coumaroyltormentic acid and 3-O-trans-p-coumaroyltormentic acid shows an inhibitory effect comparable to (-)-epigallocatechin gallate (EGCG) of green tea on the activation of Epstein-Barr virus early antigen (EBV-EA) induced by 12-O-tetradeca--noylphorbol-13-acetate (TPA).
Definition
ChEBI: 3-O-trans-p-coumaroyltormentic acid is a triterpenoid. It has a role as a metabolite.
target
Antifection | Caspase
3-O-trans-p-CouMaroyltorMentic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-O-trans-p-CouMaroyltorMentic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Labnetwork lnc. | +86-27-50766799 +8618062016861 | contact@labnetwork.com | China | 19994 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6010 | 61 |
| BioBioPha Co., Ltd. | 0871-65217109 13211707573; | y.liu@mail.biobiopha.com | China | 5654 | 65 |
| Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
| ALB Technology Limited | 702-983-3769 | sales@albtechnology.com | United States | 2993 | 55 |
| Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |