ChemicalBook >> CAS DataBase List >>1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE

CAS No.
288862-73-7
Chemical Name:
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
Synonyms
CAY10435;1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE;1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-;1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
CBNumber:
CB5423194
Molecular Formula:
C18H26N2O2
Molecular Weight:
302.41
MDL Number:
MFCD08062146
MOL File:
288862-73-7.mol
Last updated:2023-05-04 17:34:37

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Properties

Boiling point 420.9±37.0 °C(Predicted)
Density 1.044±0.06 g/cm3(Predicted)
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): .05mg/ml; Ethanol: 10 mg/ml
pka -1.77±0.50(Predicted)

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10005102 CAY10435 ≥98% 288862-73-7 500μg $53 2023-06-20 Buy
Cayman Chemical 10005102 CAY10435 ≥98% 288862-73-7 1mg $99 2023-06-20 Buy
Cayman Chemical 10005102 CAY10435 ≥98% 288862-73-7 5mg $411 2023-06-20 Buy
Cayman Chemical 10005102 CAY10435 ≥98% 288862-73-7 10mg $718 2023-06-20 Buy
AK Scientific 1312AH 1-Oxazolo[4,5-b]pyridin-2-yl-1-dodecanone 288862-73-7 5mg $564 2021-12-16 Buy
Product number Packaging Price Buy
10005102 500μg $53 Buy
10005102 1mg $99 Buy
10005102 5mg $411 Buy
10005102 10mg $718 Buy
1312AH 5mg $564 Buy

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Chemical Properties,Uses,Production

Description

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.57 nM. Using a proteonomics approach, CAY10435 was screened against the serine hydrolase family of enzymes, of which FAAH is a member. In this assay, CAY10435 exhibited IC50 values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Knowledge of the specificity of CAY10435 obtained from this experiment should allow for more accurate interpretation of results using the inhibitor in complex environments such as whole cells or animals.

Definition

ChEBI: CAY10435 is an oxazolopyridine.

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Preparation Products And Raw materials

Raw materials

Preparation Products

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
CAY10435 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one 1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl- 288862-73-7