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ChemicalBook >> CAS DataBase List >>5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid

5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid

5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid Structure
5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid structure
CAS No.
1039758-22-9
Chemical Name:
5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid
Synonyms
MK-4074;MK 4074,MK4074;5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid;sodium5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinate;3-Pyridinecarboxylic acid, 5-[1'-[(1-cyclopropyl-4-methoxy-3-methyl-1H-indol-6-yl)carbonyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]-
CBNumber:
CB63162361
Molecular Formula:
C33H31N3O6
Molecular Weight:
565.62
MDL Number:
MFCD31630723
MOL File:
1039758-22-9.mol
MSDS File:
SDS
Last updated:2023-07-14 17:38:57
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5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid Properties

Boiling point 875.4±65.0 °C(Predicted)
Density 1.43±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 83.3 mg/mL (147.27 mM)
pka 2.11±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0029249 MK-4074 99.71% 1039758-22-9 5mg $250 2021-12-16 Buy
ChemScene CS-0029249 MK-4074 99.71% 1039758-22-9 10mg $400 2021-12-16 Buy
ChemScene CS-0029249 MK-4074 99.71% 1039758-22-9 25mg $800 2021-12-16 Buy
ChemScene CS-0029249 MK-4074 99.71% 1039758-22-9 50mg $1200 2021-12-16 Buy
ChemScene CS-0029249 MK-4074 99.71% 1039758-22-9 100mg $2100 2021-12-16 Buy
Product number Packaging Price Buy
CS-0029249 5mg $250 Buy
CS-0029249 10mg $400 Buy
CS-0029249 25mg $800 Buy
CS-0029249 50mg $1200 Buy
CS-0029249 100mg $2100 Buy

5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid Chemical Properties,Uses,Production

Uses

MK-4074, strongly inhibits acetyl-CoA carboxylase, both ACC1 and ACC2 with IC50 values of approximately 3 nM. s highly liver specific because it is a substrate of organic anion transport protein (OATP) transporters that are present only in hepatocytes.

5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid Preparation Products And Raw materials

Raw materials

Preparation Products

5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
Aladdin Scientific 		+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Kaixin Chemical (Hong Kong) Limited 010-88886666-01 13112345678 loyson@tcypharm.com China 595 55
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312 liming@bio-fount.com China 9730 58
Shanghai zhigan biotechnology co., LTD zhiqianbio@126.com China 19785 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
Kaifeng Mingren Pharmaceutical Co.,LTD 0371-65741762 sales@hasunny.com China 2380 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
Aladdin Scientific 		58
Kaixin Chemical (Hong Kong) Limited 55
Fan De(Beijing) Biotechnology Co., Ltd. 58
Shanghai zhigan biotechnology co., LTD 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Shanghai hongqu biomedical technology co. LTD 58
Kaifeng Mingren Pharmaceutical Co.,LTD 58
5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinicacid sodium5-(1'-(1-cyclopropyl-4-methoxy-3-methyl-1H-indole-6-carbonyl)-4-oxospiro[chromane-2,4'-piperidin]-6-yl)nicotinate MK-4074 3-Pyridinecarboxylic acid, 5-[1'-[(1-cyclopropyl-4-methoxy-3-methyl-1H-indol-6-yl)carbonyl]-3,4-dihydro-4-oxospiro[2H-1-benzopyran-2,4'-piperidin]-6-yl]- MK 4074,MK4074 1039758-22-9