OPIPRAMOL
- CAS No.
- 315-72-0
- Chemical Name:
- OPIPRAMOL
- Synonyms
- G-33040;Nisidana;GR-33040;Opramidol;OPIPRAMOL;NSC 169867;N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene;4-(3-(DIBENZ(B,F)AZEPIN-5-YL)PROPYL)-1-PIPERAZINEETHANOL;1-Piperazineethanol, 4-3-(5H-dibenzb,fazepin-5-yl)propyl-;4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol
- CBNumber:
- CB6415167
- Molecular Formula:
- C23H29N3O
- Molecular Weight:
- 363.5
- MDL Number:
- MFCD00865455
- MOL File:
- 315-72-0.mol
| Melting point | 100-1010C |
|---|---|
| Boiling point | 494.88°C (rough estimate) |
| Density | 1.0920 (rough estimate) |
| refractive index | 1.6500 (estimate) |
| storage temp. | -20°C Freezer |
| solubility | Acetonitrile: slightly soluble; Chloroform: slightly soluble; Methanol: slightly soluble |
| pka | pKa 8(H2O,t =25,I=0.01(NaCl)) (Uncertain) |
| BRN | 627076 |
| FDA UNII | D23ZXO613C |
| ATC code | N06AA05 |
OPIPRAMOL price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29471 | Opipramol | 315-72-0 | 5mg | $39 | 2024-03-01 | Buy |
| Cayman Chemical | 29471 | Opipramol | 315-72-0 | 10mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 29471 | Opipramol | 315-72-0 | 25mg | $152 | 2024-03-01 | Buy |
| TRC | O669600 | Opipramol | 315-72-0 | 10mg | $155 | 2021-12-16 | Buy |
| TRC | O669600 | Opipramol | 315-72-0 | 5mg | $105 | 2021-12-16 | Buy |
OPIPRAMOL Chemical Properties,Uses,Production
Chemical Properties
Crystalline Solid
Originator
Insidon,Geigy,W. Germany,1962
Uses
Antidepressant; antipsychotic
Definition
ChEBI: 2-[4-[3-(11-benzo[b][1]benzazepinyl)propyl]-1-piperazinyl]ethanol is a dibenzoazepine.
Manufacturing Process
A solution of 5-(3-toluene-p-sulfonyloxypropyl)dibenzazepine (9.2g) and 1-(2hydroxyethyl)piperazine (8.6g) in anhydrous toluene (50 cc) is heated at boiling point under reflux for 4 hours.
After cooling, distilled water (75 cc) is added. The aqueous phase is decanted. The toluene solution is washed with distilled water (25 cc) and then extracted with N hydrohloric acid (40 cc). The hydrochloric acid solution is made alkaline to phenolphthalein with sodium hydroxide (d = 1.33).The base which separates is extracted with chloroform (50 cc). The chloroform solution is dried over anhydrous sodium sulfate and then evaporated to dryness. There are obtained 5-[3-(4-β-hydroxyethylpiperazino)propyl]dibenzazepine (7.95g), the dihydrochloride of which, crystallized from ethanol, melts at about 210°C.
Therapeutic Function
Antidepressant, Antipsychotic
OPIPRAMOL Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 94838 | 76 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
| China Langchem Inc. | 0086-21-58956006 | China | 7815 | 57 | |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9709 | 58 |