Jacobine.
- CAS No.
- 6870-67-3
- Chemical Name:
- Jacobine.
- Synonyms
- Jacobine.;NSC-89936;(20S)-15α,20-Epoxy-15,20-dihydro-12-hydroxysenecionan-11,16-dione;(15R,20S)-15,20-Dihydro-15,20-epoxy-12-hydroxysenecionan-11,16-dione;Spiro[[1,6]dioxacyclododecino[2,3,4-gh]pyrrolizine-3(2H),2'-oxirane]-2,7(4H)-dione, 5,6,9,11,13,14,14a,14b-octahydro-6-hydroxy-3',5,6-trimethyl-, (2'S,3'S,5R,6R,14aR,14bR)-
- CBNumber:
- CB71248363
- Molecular Formula:
- C18H25NO6
- Molecular Weight:
- 351.39
- MDL Number:
- MFCD00870079
- MOL File:
- 6870-67-3.mol
- MSDS File:
- SDS
Melting point | 228°C |
---|---|
Boiling point | 485.2°C (rough estimate) |
Density | 1.2737 (rough estimate) |
refractive index | 1.5100 (estimate) |
pka | 12.89±0.60(Predicted) |
FDA UNII | GM32U80H1R |
IARC | 3 (Vol. 10, Sup 7) 1987 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264-P270-P301+P312-P330-P501 |
RIDADR | 1544 |
HazardClass | 6.1(b) |
PackingGroup | III |
Jacobine. price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | J210395 | Jacobine | 6870-67-3 | 0.25mg | $160 | 2021-12-16 | Buy |
TRC | J210395 | Jacobine | 6870-67-3 | 0.5mg | $305 | 2021-12-16 | Buy |
TRC | J210395 | Jacobine | 6870-67-3 | 1mg | $570 | 2021-12-16 | Buy |
Biosynth Carbosynth | BJ161539 | Jacobine | 6870-67-3 | 10mg | $900 | 2021-12-16 | Buy |
Biosynth Carbosynth | BJ161539 | Jacobine | 6870-67-3 | 25mg | $1875 | 2021-12-16 | Buy |
Jacobine. Chemical Properties,Uses,Production
Description
This alkaloid of the pyrrolizidine group of bases occurs in Senecio cineraria D.C., S. crucifolia and S. Jacobea. It is a laevorotatory base with [α]17D - 46.3° (CHCl 3 ). The alkaloid forms crystalline salts and derivatives, e.g. the hydrochloride, m.p. 220°C; [α]19D - 14.3° (H20); nitrate, m.p. 234°C; methiodide, m.p. 255°C and the picrate, m.p. 180°C which is soluble in H20. The alkaloid contains two active hydrogens and on alkaline hydrolysis yields retronecine and jaconecic acid, ClOH16 0 6, m.p. 182°C; [α]25D + 31.7° containing three O-methyl groups
Uses
Jacobine is a pyrrolizidine alkaloid which has been shown to be an herbivore insect deterrent and may be used in the protection of vegetation. Extracted from Crassocephalum plant of West Africa.
Definition
ChEBI: Jacobine is a pyrrolizine alkaloid.
References
Manske., Can. J. Res., 5,651 (1931)
Hosking, Brandt., New Zealand J. Sci. Tech., 14,638 (1936)
Blackie.,Pharrn. J., 138,102 (1937)
Barger, Blackie., J. Chern. Soc., 584 (1937)
Bradbury, Willis., Austral. J. Chern., 9,258 (1956)
Geissman., ibid, 12,247 (1959)
Bradbury, Masamune., J. Arner. Chern. Soc., 81,5201 (1959)
Masamune., ibid, 82, 5253 (1960)
Freidrichsons, Mathieson, Sutor., Tetrahedron Lett., 35 (1960)
Jacobine. Preparation Products And Raw materials
Raw materials
Preparation Products
Jacobine. Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7887 | 56 |
Wuxi Zhongkun Biochemical Technology Co., Ltd. | 0510-85629785 18013409632 | sales@reading-chemicals.com | China | 15185 | 58 |
Wuhan ChemFaces Biochemical Co., Ltd. | 18607101326 15172504745 | aileen@chemfaces.com | China | 7059 | 55 |
Biyu Biotechnology (Shanghai) Co., ltd | 021-26018599 | China | 270 | 56 | |
EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
Chengdu Push Bio-Technology Co., Ltd. | 028-85370565-229 18080489829 | 3004654993@qq.com | China | 9266 | 60 |
Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9303 | 58 |
Nanjing Digger Medical Technology Co. Ltd. | 025-025-51191215 18013836722 | 2399235533@qq.com | China | 4933 | 58 |