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Flavanomarein

CAS No.
577-38-8
Chemical Name:
Flavanomarein
Synonyms
FLAVANOMAREIN;FLAVANOMAREIN hplc;TRIHYDROXYFLAVANONE;ISOOKANIN-7-GLUCOSIDE;FLAVANOMAREIN WITH HPLC;ISOOKANIN-7-O-GLUCOSIDE;FLAVANOMAREIN USP/EP/BP;7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE;3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE;(S)-2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one
CBNumber:
CB7144422
Molecular Formula:
C21H22O11
Molecular Weight:
450.39
MDL Number:
MFCD00136058
MOL File:
577-38-8.mol
Last updated:2023-09-04 16:42:00

Flavanomarein Properties

Melting point 243-246°C
Boiling point 818.2±65.0 °C(Predicted)
Density 1.665±0.06 g/cm3(Predicted)
pka 7.58±0.40(Predicted)
LogP -1.080 (est)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271
Hazard Codes  Xi

Flavanomarein price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Arctom CFN91006 Flavanomarein 577-38-8 5mg $328 2021-12-16 Buy
Product number Packaging Price Buy
CFN91006 5mg $328 Buy

Flavanomarein Chemical Properties,Uses,Production

Chemical Properties

Flavanomarein, known as isookanin-7-o-glucoside, is a dihydroflavonoid isolated from the ethanolic extract of Coreopsistinctoria and is considered to be one of the active ingredients of the herb with a wide range of pharmacological effects, but there are not many studies on the in vitro and in vivo pharmacokinetics of flavanomarein.

Uses

Flavanomarein is a predominant flavonoid of Coreopsis tinctoria Nutt with protective effects against diabetic nephropathy. Flavanomarein has good antioxidative, antidiabetic, antihypertensive and anti-hyperlipidemic activities.
Flavanomarein inhibits high glucose-stimulated epithelialmesenchymal transition in HK-2 cells via targeting spleen tyrosine kinase

Flavanomarein Preparation Products And Raw materials

Raw materials

Preparation Products

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Flavanomarein Spectrum

TRIHYDROXYFLAVANONE 7-O-GLUCOSYL-4',5',8-TRIHYDROXYFLAVANONE FLAVANOMAREIN ISOOKANIN-7-GLUCOSIDE ISOOKANIN-7-O-GLUCOSIDE (S)-2-(3,4-dihydroxyphenyl)-7-(beta-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one FLAVANOMAREIN WITH HPLC FLAVANOMAREIN hplc 3',4',7,8-TETRAHYDROXYFLAVANONE-7-O-GLUCOSIDE (S)-2-(3,4-Dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-4H-1-benzopyran-4-one (2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2,3-dihydrochromen-4-one (2S)-2-(3,4-dihydroxyphenyl)-8-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-chroman-4-one 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-7-(β-D-glucopyranosyloxy)-2,3-dihydro-8-hydroxy-, (2S)- FLAVANOMAREIN USP/EP/BP antioxidative,PI3K,antihypertensive,Smad,anti-hyperlipidemic,Flavanomarein,6-hydroxydopamine,NF-κB,TGF-β1,diabetic,nephropathy,inhibit,Inhibitor,AKT,Syk,antidiabetic 577-38-8 reagent Flavanones