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ChemicalBook >> CAS DataBase List >>(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Structure
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol structure
CAS No.
289893-25-0
Chemical Name:
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol
Synonyms
Pefcalcitol;Amrioclomol;arimoclomol;BRX-220 free base;(2R-)Arimoclomol NEW;(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol;3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide;aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor
CBNumber:
CB71480024
Molecular Formula:
C14H20ClN3O3
Molecular Weight:
313.78
MDL Number:
MFCD16660939
MOL File:
289893-25-0.mol
MSDS File:
SDS
Last updated:2023-06-08 09:03:09
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(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Properties

Melting point 93 - 95o C
Boiling point 539.2±60.0 °C(Predicted)
Density 1.32±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
form Solid
pka 14.03±0.20(Predicted)
color White to Off-White
Stability Hygroscopic
FDA UNII EUT3557RT5

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
Hazard statements  H261
Precautionary statements  P223-P231+P232-P280-P335+P334-P370+P378-P402+P404-P501
NFPA 704
0
0 2

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A771278 Arimoclomol 289893-25-0 1mg $110 2021-12-16 Buy
Biosynth Carbosynth FA30834 (2R-)Arimoclomol NEW 289893-25-0 5mg $175 2021-12-16 Buy
Biosynth Carbosynth FA30834 (2R-)Arimoclomol NEW 289893-25-0 10mg $300 2021-12-16 Buy
Biosynth Carbosynth FA30834 (2R-)Arimoclomol NEW 289893-25-0 25mg $475 2021-12-16 Buy
American Custom Chemicals Corporation API0007198 AMRIOCLOMOL 95.00% 289893-25-0 100MG $2732.5 2021-12-16 Buy
Product number Packaging Price Buy
A771278 1mg $110 Buy
FA30834 5mg $175 Buy
FA30834 10mg $300 Buy
FA30834 25mg $475 Buy
API0007198 100MG $2732.5 Buy

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Chemical Properties,Uses,Production

Uses

Arimoclomol is a co-inducer of HSP that acts through heat shock factor 1 (HSF1) in cells undergoing cellular stress. Has therapeutic potential in motor neuron degenerative diseases. Potential treatment for liposomal storage disorders, such as Niemann-Pick disease type C.

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21689 55
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		+86-18341751992 +86-15382112998 757984502@qq.com China 892 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139 orders@jknbiochem.com China 4604 58
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4271 65
Hangzhou J&H Chemical Co., Ltd. +86-571-87396432 sales@jhechem.com China 10015 53
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
BioPharmaMatrix,Inc. 0510-86010668 sales@biopharmamatrix.com China 3716 55
Supplier Advantage
Henan Tianfu Chemical Co.,Ltd. 		55
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd 		58
LEAPCHEM CO., LTD. 		58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		58
Shanghai Ennopharm Co., Ltd. 65
Hangzhou J&H Chemical Co., Ltd. 53
Shanghai EFE Biological Technology Co., Ltd. 58
BioPharmaMatrix,Inc. 55

289893-25-0((2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol)Related Search:

Aprepitant
(2R)-1-[[chloro-(1-oxidopyridin-5-yl)methylidene]amino]oxy-3-(1-piperidyl)propan-2-ol arimoclomol Amrioclomol Pefcalcitol (2R-)Arimoclomol NEW BRX-220 free base 3-Pyridinecarboximidoyl chloride, N-[(2R)-2-hydroxy-3-(1-piperidinyl)propoxy]-, 1-oxide aggregation,Heat shock proteins,HSP,co-inducer,system,BRX220,motor,Arimoclomol,inhibit,ubiquitin,BRX 220,neurons,misfolded,proteasome,BRX-220,protein,assemblies,clearance,Inhibitor 289893-25-0