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Biphenylindanone A

Biphenylindanone A structure

CAS No.: 866823-73-6

Chemical Name:: Biphenylindanone A

Synonyms: BINA;CS-203;MRLSD 230;BINA, >=98%;Biphenylindanone A;4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid;3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid;3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylicacid;[1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-diMethyl-1-oxo-1H-inden-5-yl)oxy]Methyl]-

CBNumber:: CB72518270

Molecular Formula:: C30H30O4

Molecular Weight:: 454.56

MDL Number:: MFCD19440914

MOL File:: 866823-73-6.mol

Last updated:2023-06-30 15:45:59

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Biphenylindanone A Properties

Melting point	238-241℃
Boiling point	676.9±55.0 °C(Predicted)
Density	1.220
storage temp.	Desiccate at RT
solubility	DMSO: ≥18mg/mL
pka	4.17±0.10(Predicted)
form	powder
color	white to tan

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
WGK Germany	3

Biphenylindanone A price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	5.04463	BINA - CAS 866823-73-6 - Calbiochem	866823-73-6	5mg	$257	2023-01-07	Buy
Sigma-Aldrich	B8688	Biphenyl-indanone A ≥98% (HPLC), powder	866823-73-6	5mg	$181	2022-05-15	Buy
Sigma-Aldrich	B8688	Biphenyl-indanone A ≥98% (HPLC), powder	866823-73-6	25mg	$694	2022-05-15	Buy
Cayman Chemical	11986	Biphenylindanone A ≥98%	866823-73-6	5mg	$106	2024-03-01	Buy
Cayman Chemical	11986	Biphenylindanone A ≥98%	866823-73-6	10mg	$184	2024-03-01	Buy

Product number	Packaging	Price	Buy
5.04463	5mg	$257	Buy
B8688	5mg	$181	Buy
B8688	25mg	$694	Buy
11986	5mg	$106	Buy
11986	10mg	$184	Buy

Biphenylindanone A Chemical Properties,Uses,Production

Description

The metabotropic glutamate receptor 2 (mGluR2) is a G_i/o-coupled receptor which is expressed on presynaptic nerve terminals and modulates the release of neurotransmitters like glutamate and GABA. Biphenylindanone A (BINA) is a positive allosteric modulator of mGluR2, stimulating the human and rat receptors with EC₅₀ values of 33.2 and 96 nM, respectively. It has no effect on glutamate-induced activation of other mGluR types. BINA can be used on cells, tissues, or animals. Because of its selectivity for mGluR2, robust in vivo activity, and brain penetrance, BINA can be used to elucidate the role of mGluR2 in such diverse processes as psychosis, schizophrenia, and drug addiction.

Uses

Biphenylindanone A is an orally active metabotropic glutamate subtype 2 receptor positive allosteric modulator.

Definition

ChEBI: Biphenylindanone a is a member of biphenyls.

storage

Room temperature (desiccate)

Biphenylindanone A Preparation Products And Raw materials

Raw materials

Preparation Products

Biphenylindanone A Suppliers

Global( 55)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	94838	76
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
ZHIWE CHEMTECH CO LTD	021-20221225 13917446399	sales@zhiwe.net	China	580	61
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Nanjing JinruiJiuAn Biotechnology Co., Ltd.	025-58196018 800028039	sales@fartop.net	China	2231	55

Supplier	Advantage
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
ZHIWE CHEMTECH CO LTD	61
VDM Biochemicals	64
Nanjing JinruiJiuAn Biotechnology Co., Ltd.	55

View Lastest Price from Biphenylindanone A manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2020-01-15	Biphenylindanone A 866823-73-6	US $1.00 / KG	1KG	99.0%	100kg	Career Henan Chemical Co

Biphenylindanone A
866823-73-6
US $1.00 / KG
99.0%
Career Henan Chemical Co

Biphenylindanone A 3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylicacid BINA 3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid MRLSD 230 [1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-diMethyl-1-oxo-1H-inden-5-yl)oxy]Methyl]- BINA, >=98% 4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid CS-203 866823-73-6 C30H30O4