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ChemicalBook >> CAS DataBase List >> Biphenylindanone A

Biphenylindanone A

Biphenylindanone A price.
  • $106 - $3300
  • Product name: Biphenylindanone A
  • CAS: 866823-73-6
  • MF: C30H30O4
  • MW: 454.56
  • EINECS:-0
  • MDL Number:MFCD19440914
  • Synonyms:Biphenylindanone A;3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylicacid;BINA;3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid;MRLSD 230;[1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-diMethyl-1-oxo-1H-inden-5-yl)oxy]Methyl]-;BINA, >=98%;4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid
17 prices
Selected condition:
Brand
  • AK Scientific
  • ApexBio Technology
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 003
  • 1mg
  • 50
  • 5mg
  • 10mg
  • 25mg
  • ManufacturerAK Scientific
  • Product numberY0350
  • Product descriptionBiphenyl-indanone A
  • Packaging5mg
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7575
  • Product descriptionBINA
  • Packaging5mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7575
  • Product descriptionBINA
  • Packaging10mg
  • Price$208
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7575
  • Product descriptionBINA
  • Packaging25mg
  • Price$486
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11986
  • Product descriptionBiphenylindanone A ≥98%
  • Packaging5mg
  • Price$106
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11986
  • Product descriptionBiphenylindanone A ≥98%
  • Packaging10mg
  • Price$184
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11986
  • Product descriptionBiphenylindanone A ≥98%
  • Packaging25mg
  • Price$427
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0006671
  • Product descriptionBiphenyl-indanone A ≥99.0%
  • Packaging1mg
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0006671
  • Product descriptionBiphenyl-indanone A ≥99.0%
  • Packaging5mg
  • Price$395
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product number013031
  • Product descriptionBiphenyl-indanone A
  • Packaging003
  • Price$3300
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB8688
  • Product descriptionBiphenyl-indanone A ≥98% (HPLC), powder
  • Packaging5mg
  • Price$181
  • Updated2022-05-15
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number5.04463
  • Product descriptionBINA - CAS 866823-73-6 - Calbiochem
  • Packaging5mg
  • Price$257
  • Updated2023-01-07
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB8688
  • Product descriptionBiphenyl-indanone A ≥98% (HPLC), powder
  • Packaging25mg
  • Price$694
  • Updated2022-05-15
  • Buy
  • ManufacturerTocris
  • Product number4048
  • Product descriptionBINA ≥98%(HPLC)
  • Packaging10
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number4048
  • Product descriptionBINA ≥98%(HPLC)
  • Packaging50
  • Price$943
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberB397910
  • Product descriptionBiphenyl-indanone A
  • Packaging10mg
  • Price$140
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0350 Biphenyl-indanone A 5mg $159 2021-12-16 Buy
ApexBio Technology B7575 BINA 5mg $118 2021-12-16 Buy
ApexBio Technology B7575 BINA 10mg $208 2021-12-16 Buy
ApexBio Technology B7575 BINA 25mg $486 2021-12-16 Buy
Cayman Chemical 11986 Biphenylindanone A ≥98% 5mg $106 2024-03-01 Buy
Cayman Chemical 11986 Biphenylindanone A ≥98% 10mg $184 2024-03-01 Buy
Cayman Chemical 11986 Biphenylindanone A ≥98% 25mg $427 2024-03-01 Buy
ChemScene CS-0006671 Biphenyl-indanone A ≥99.0% 1mg $130 2021-12-16 Buy
ChemScene CS-0006671 Biphenyl-indanone A ≥99.0% 5mg $395 2021-12-16 Buy
DC Chemicals 013031 Biphenyl-indanone A 003 $3300 2021-12-16 Buy
Sigma-Aldrich B8688 Biphenyl-indanone A ≥98% (HPLC), powder 5mg $181 2022-05-15 Buy
Sigma-Aldrich 5.04463 BINA - CAS 866823-73-6 - Calbiochem 5mg $257 2023-01-07 Buy
Sigma-Aldrich B8688 Biphenyl-indanone A ≥98% (HPLC), powder 25mg $694 2022-05-15 Buy
Tocris 4048 BINA ≥98%(HPLC) 10 $225 2021-12-16 Buy
Tocris 4048 BINA ≥98%(HPLC) 50 $943 2021-12-16 Buy
TRC B397910 Biphenyl-indanone A 10mg $140 2021-12-16 Buy

Properties

Melting point :238-241℃
Boiling point :676.9±55.0 °C(Predicted)
Density :1.220
storage temp. :Desiccate at RT
solubility :DMSO: ≥18mg/mL
pka :4.17±0.10(Predicted)
form :powder
color :white to tan

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The metabotropic glutamate receptor 2 (mGluR2) is a Gi/o-coupled receptor which is expressed on presynaptic nerve terminals and modulates the release of neurotransmitters like glutamate and GABA. Biphenylindanone A (BINA) is a positive allosteric modulator of mGluR2, stimulating the human and rat receptors with EC50 values of 33.2 and 96 nM, respectively. It has no effect on glutamate-induced activation of other mGluR types. BINA can be used on cells, tissues, or animals. Because of its selectivity for mGluR2, robust in vivo activity, and brain penetrance, BINA can be used to elucidate the role of mGluR2 in such diverse processes as psychosis, schizophrenia, and drug addiction.