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(R)-4-Benzyl-2-oxazolidinone

CAS No.
102029-44-7
Chemical Name:
(R)-4-Benzyl-2-oxazolidinone
Synonyms
(R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE;RBOX;4-benzyl-2-0xazolidinone;(4R)-Phenylmethyl-2-oxazolidinone;R-BOZ;MLS00;TB-2044;TL806371;-2-oxazoL;(R)-4-BenzyL
CBNumber:
CB7852611
Molecular Formula:
C10H11NO2
Molecular Weight:
177.2
MDL Number:
MFCD00010846
MOL File:
102029-44-7.mol
MSDS File:
SDS
Last updated:2024-08-21 22:41:43

(R)-4-Benzyl-2-oxazolidinone Properties

Melting point 88-90 °C
alpha 62 º (C=1, CHCl3)
Boiling point 309.12°C (rough estimate)
Density 1.1607 (rough estimate)
refractive index 14.5 ° (C=5, MeOH)
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Slightly)
form Crystalline Powder
pka 12.78±0.40(Predicted)
color White to almost white
optical activity [α]18/D +64°, c = 1 in chloroform
Water Solubility Insoluble in water. Soluble in Chloroform.
Sensitive Hygroscopic
BRN 4782551
CAS DataBase Reference 102029-44-7(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H320
Precautionary statements  P264-P305+P351+P338+P337+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  22-24/25-36-26
WGK Germany  3
3-10
HS Code  29349990
NFPA 704
1
2 0

(R)-4-Benzyl-2-oxazolidinone price More Price(63)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 300977 (R)-4-Benzyl-2-oxazolidinone 99% 102029-44-7 5g $24.68 2024-03-01 Buy
Sigma-Aldrich 300977 (R)-4-Benzyl-2-oxazolidinone 99% 102029-44-7 1G $35.8 2023-01-07 Buy
TCI Chemical B1786 (R)-4-Benzyl-2-oxazolidinone >98.0%(GC) 102029-44-7 5g $92 2024-03-01 Buy
TCI Chemical B1786 (R)-4-Benzyl-2-oxazolidinone >98.0%(GC) 102029-44-7 25g $297 2024-03-01 Buy
Alfa Aesar A16770 (R)-(+)-4-Benzyl-2-oxazolidinone, 99% 102029-44-7 1g $40.65 2024-03-01 Buy
Product number Packaging Price Buy
300977 5g $24.68 Buy
300977 1G $35.8 Buy
B1786 5g $92 Buy
B1786 25g $297 Buy
A16770 1g $40.65 Buy

(R)-4-Benzyl-2-oxazolidinone Chemical Properties,Uses,Production

Description

(R)-4-Benzyl-2-oxazolidinone is a derivative of oxazolidinone. It can be used in the preparation of enantiopure carbocyclic nucleosides, which act as a HIV protease inhibitor. It can also be used as a chiral auxiliary in the enantioselective synthesis of (2R, 2′S)-erythro-methylphenidate, beta-lactams and alpha-amino acids. Its end product includes asymmetric single isomeric drugs such as antitumor, anesthetic and entipasmodic products.

Chemical Properties

white to light yellow crystal powde

Uses

(R)-(+)-4-Benzyl-2-oxazolidinones are used in the enantioselective synthesis of beta-lactams and alpha-amino acids. End products can include asysmmetric single isomeric drugs of antitumor, anesthetic, antipasmodic products. Used in the synthesis of HIV protease inhibitors. An oxazolidinone used in chiral auxiliary asymetric synthesis.

Uses

intermediate for Aliskiren hemifumarate, Darifenacin HBr, Zolmitriptan

References

http://www.sigmaaldrich.com/catalog/product/aldrich/300977? lang=en®ion=US
https://www.alfa.com/en/catalog/A16770/ Shieh, Wen Chung, et al. "Synthesis of enantiomerically enriched 4- piperidinylglycine." US, US 6670477B2. 2003.

(R)-4-Benzyl-2-oxazolidinone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 547)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578 sales@hbmojin.com China 12446 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325 sales1@chuanghaibio.com China 5882 58
hebei hongtan Biotechnology Co., Ltd
+86-86-1913198-3935 +8617331935328 sales03@chemcn.cn China 973 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29798 60
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+86-371-66670886 info@dakenam.com China 18628 58
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025-84209270 15906146951 CHINA 115 55
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21667 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070 product@chemlin.com.cn CHINA 3012 60
Zjartschem
+86-571 87238903 jocelynpan@zjarts.com CHINA 993 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29888 58

View Lastest Price from (R)-4-Benzyl-2-oxazolidinone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(R)-4-Benzyl-2-oxazolidinone pictures 2024-09-23 (R)-4-Benzyl-2-oxazolidinone
102029-44-7
US $9.00 / KG 1KG 99.9 1 ton Hebei Chuanghai Biotechnology Co,.LTD
(R)-4-Benzyl-2-oxazolidinone pictures 2024-09-23 (R)-4-Benzyl-2-oxazolidinone
102029-44-7
US $0.00 / kg 1kg 99%min 20ton Jinan Jianfeng Chemical Co., Ltd
(R)-4-Benzyl-2-oxazolidinone pictures 2024-09-23 (R)-4-Benzyl-2-oxazolidinone
102029-44-7
US $50.00 / kg 1kg 99% 1000 hebei hongtan Biotechnology Co., Ltd
(R)-4-BENZYL-2-OXAZOLIDINONE HPLC 99+% (R)-4-BENZYL-2-OXAZOLIDINONE 98.0% (4R)-4-(Phenylmethyl)-1,3-oxazolidin-2-one (4R)-4-(Phenylmethyl)-2-oxazolidinone (4R)-Benzyloxazolidin-2-one (R)-(+)-4-BENZYL-2-OXAZOLIDINONE FOR SYN (R)-(+)-4-Benzyl-2-oxazolidinone≥ 99.5% (HPLC, Chiral purity) R-BOZ (4R)-4-Benzyl-2-oxo-1,3-oxazolidine, (4R)-4-(Phenylmethyl)-1,3-oxazolidin-2-one (R)-4-Benzyl-2-oxazolidinone 99% (R)-4-Benzyl-2-oxazolidinone, 99%, ee:>99% (R)-4-Benzyl-2-oxazolidinone, >99% ee (R)-4-Benzyl-2-oxazolidinone,99%,>99% ee (R)-4-Benzyl-2-0xazolidinone (R)-(+)-4-Benzyl-2-xazolidineone (R)-4-Benzyl-2-oxazo (R)-4-Benzyl-2-oxazolidinone,99% (4R)-4-Benzyl-2-oxo-1,3-oxazolidine 2-OXAZOLIDINONE, 4-(PHENYLMETHYL)-, (4R)- 2-OXAZOLIDINONE, 4-PHENYL-, (4R)- (4R)-4-BENZYL-1,3-OXAZOLIDIN-2-ONE (4R)-4-BENZYLOXAZOLIDIN-2-ONE (4R)-4-PHENYL-1,3-OXAZOLIDIN-2-ONE (4R)-4-PHENYLOXAZOLIDIN-2-ONE 4-R-BENZYL-2-OXAZOLIDINONE (4R)-PHENYL-2-OXAZOLIDINONE (R)-PH-OXAZOLIDINONE (R)-4-BENZYL-OXAZOLIDIN-2-ONE (R)-(+)-4-BENZYL-2-OXAZOLIDINONE (R)-4-BENZYL-2-OXAZOLIDINONE (R)-(+)-4-BENZYL-2-OXAZOLIDONE (R)-(+)-4-Benzyl-2-oxazolidinone (R)-4-BenzyL (R)-4-Benzyl-2-oxazolidinone > -2-oxazoL (R)-4-Benzyl-2-oxazolidinone USP/EP/BP 4-benzyl-2-0xazolidinone (4R)-Phenylmethyl-2-oxazolidinone RBOX (R)-4-(PHENYLMETHYL)-2-OXAZOLIDINONE (R)-4-Benzyl-2-oxazolidinone CAS No. 102029-44-7 MLS00 OJOFMLDBXPDXLQ-SECBINFHSA-N TL806371 TB-2044 (R)-Solriamfetol Impurity 5 102029-44-7 102021-44-7 99319-52-1 102090-44-7 1022029-44-7 101029-44-7 Chiral Building Blocks Asymmetric Synthesis Glycidyl Compounds, etc. (Chiral) Chiral Auxiliaries Oxazolidinone Derivatives Asymmetric Synthesis