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ChemicalBook >> CAS DataBase List >>N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Structure
N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride structure
CAS No.
883976-12-3
Chemical Name:
N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride
Synonyms
M8-B;M8-B hydrochloride;M8-B hydrochloride >=98% (HPLC);M8 B Hydrochloride,M-8-B Hydrochloride,M8B Hydrochloride;N-(2-Aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide hydrochloride;N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride;2-Thiophenecarboxamide, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, monohydrochloride
CBNumber:
CB82750701
Molecular Formula:
C22H25ClN2O3S
Molecular Weight:
432.9635
MDL Number:
MFCD27978374
MOL File:
883976-12-3.mol
Last updated:2023-09-20 16:43:00
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N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Properties

storage temp. 2-8°C
solubility H2O: soluble2mg/mL, clear (warmed)
form powder
color white to beige

SAFETY

Risk and Safety Statements

WGK Germany  3

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SML0893 M8-B hydrochloride ≥98% (HPLC) 883976-12-3 5mg $118 2024-03-01 Buy
Sigma-Aldrich SML0893 M8-B hydrochloride ≥98% (HPLC) 883976-12-3 25mg $478 2024-03-01 Buy
Cayman Chemical 21646 M8-B (hydrochloride) ≥98% 883976-12-3 1mg $32 2024-03-01 Buy
Cayman Chemical 21646 M8-B (hydrochloride) ≥98% 883976-12-3 5mg $100 2024-03-01 Buy
Cayman Chemical 21646 M8-B (hydrochloride) ≥98% 883976-12-3 10mg $139 2024-03-01 Buy
Product number Packaging Price Buy
SML0893 5mg $118 Buy
SML0893 25mg $478 Buy
21646 1mg $32 Buy
21646 5mg $100 Buy
21646 10mg $139 Buy

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Chemical Properties,Uses,Production

Description

M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin , or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively). It displays no effect at other TRP channels. M8-B decreases deep body temperature in wild-type mice and rats but has no effect on body temperature in TRPM8 KO mice.

Uses

M8 B Hydrochloride is a channel blocker of cold receptor TRPM8.

storage

Store at +4°C

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Suppliers

Global( 40)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
TargetMol Chemicals Inc. 		+1-781-999-5354 support@targetmol.com United States 19973 58
Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525 masar@topule.com China 8474 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 14059 65
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216 info@yuhaochemical.com China 2031 58
Chengdu Kamel Pharmaceutical Co., Ltd 028-67136579 15828051124 sales@kamelpharm.com China 1751 55
Pharmacodia (Beijing) Co.,Ltd +86-400-851-9921 sales@pharmacodia.com China 2317 55
Supplier Advantage
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
TargetMol Chemicals Inc. 		58
Wuhan Topule Biopharmaceutical Co., Ltd 		58
LEAPCHEM CO., LTD. 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
BOC Sciences 65
HangZhou YuHao Chemical Technology Co., Ltd. 58
Chengdu Kamel Pharmaceutical Co., Ltd 55
Pharmacodia (Beijing) Co.,Ltd 55

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride Spectrum

N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride(883976-12-3)1HNMR
M8-B hydrochloride N-(2-Aminoethyl)-N-(4-(benzyloxy)-3-methoxybenzyl)thiophene-2-carboxamide hydrochloride N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-2-thiophenecarboxamide hydrochloride 2-Thiophenecarboxamide, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, monohydrochloride M8-B M8-B hydrochloride >=98% (HPLC) M8 B Hydrochloride,M-8-B Hydrochloride,M8B Hydrochloride 883976-12-3