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Mirin

Mirin structure

CAS No.: 1198097-97-0

Chemical Name:: Mirin

Synonyms: CS-2593;(Z)-Mirin;(Z)-Mirin,Inhibitor,(Z)Mirin,(Z) Mirin,inhibit;(Z)-2-Amino-5-(4-hydroxybenzylidene)thiazol-4(5H)-one;(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone;4(5H)-Thiazolone, 2-amino-5-[(4-hydroxyphenyl)methylene]-, (5Z)-;(5Z) -2-amino-5- [(4-hydroxyphenyl) methylene] -4 (5H) - thiazolidone

CBNumber:: CB83037397

Molecular Formula:: C10H8N2O2S

Molecular Weight:: 220.25

MDL Number:: MFCD05885480

MOL File:: 1198097-97-0.mol

Last updated:2023-09-04 15:50:00

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Mirin Properties

Boiling point	441.6±55.0 °C(Predicted)
Density	1.49±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	insoluble in EtOH; insoluble in H2O; ≥9.3 mg/mL in DMSO
form	solid
pka	8.70±0.30(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H319-H315
Precautionary statements	P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

Mirin price More Price(17)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	M364938	Mirin	1198097-97-0	50mg	$225	2021-12-16	Buy
ApexBio Technology	B5389	Mirin	1198097-97-0	50mg	$228	2021-12-16	Buy
American Custom Chemicals Corporation	INB0004757	2-AMINO-5-[(4-HYDROXYPHENYL)METHYLENE]-, (5Z)-4(5H)-THIAZOLONE 95.00%	1198097-97-0	5MG	$502.78	2021-12-16	Buy
ApexBio Technology	B5389	Mirin	1198097-97-0	10mM(in 1mL DMSO)	$50	2021-12-16	Buy
ApexBio Technology	B5389	Mirin	1198097-97-0	10mg	$83	2021-12-16	Buy

Product number	Packaging	Price	Buy
M364938	50mg	$225	Buy
B5389	50mg	$228	Buy
INB0004757	5MG	$502.78	Buy
B5389	10mM(in 1mL DMSO)	$50	Buy
B5389	10mg	$83	Buy

Mirin Chemical Properties,Uses,Production

Uses

Mirin is an MRN-ATM pathway inhibitor blocking 3’ and 5’ exonuclease activity associated with Mre11, inducing G2 cell cycle arrest.

Biological Activity

mirin is a potent mrn complex inhibitor. mirin inhibits mre11-associated exonuclease activity, rather than alters dna-binding or mrn complex formation. moreover, mirin prevents mrn-dependent activation of atm in response to dna double-strand breaks, with an ic50 value of 12 μm. the mrn complex acts as a dna damage sensor, responsible for maintaining genome stability during dna replication, promoting homology-dependent dna repair and activating atm. the mrn-atm pathway plays an essential role in sensing and signaling from dna double-strand breaks.1. dupré a, boyer-chatenet l, sattler rm, et al. a forward chemical genetic screen reveals an inhibitor of the mre11-rad50-nbs1 complex. nature chemical biology, 2008, 4(2): 119-125.

storage

Store at +4°C

Mirin synthesis

Synthesis of Mirin from 4-Hydroxybenzaldehyde and Pseudothiohydantoin

Mirin Preparation Products And Raw materials

Raw materials

4-HYDROXYBENZYLIDENEMALONONITRILE Pseudothiohydantoin 4-Hydroxybenzaldehyde

Preparation Products

Mirin Suppliers

Global( 83)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Haibo Biotechnology Co., Ltd	+undefined18602966907	qinhe02@xaltbio.com	China	1000	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5738	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	+8618829768577	gao490372054@gamil.com	China	1250	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58

Supplier	Advantage
Shaanxi Haibo Biotechnology Co., Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Nantong HI-FUTURE Biology Co., Ltd.	58

View Lastest Price from Mirin manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-04-12	Mirin 1198097-97-0	US $0.00 / kg	1kg	99%	2000ton	Shaanxi Haibo Biotechnology Co., Ltd
	2019-09-06	(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone 1198097-97-0	US $1.00 / ASSAYS	1ASSAYS	95%~99%	per week:100kg	Career Henan Chemical Co

Mirin
1198097-97-0
US $0.00 / kg
99%
Shaanxi Haibo Biotechnology Co., Ltd

(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone
1198097-97-0
US $1.00 / ASSAYS
95%~99%
Career Henan Chemical Co

Mirin Spectrum

Mirin(1198097-97-0)MS Mirin(1198097-97-0)¹HNMR

1198097-97-0(Mirin)Related Search:

Phenol 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione (5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione

(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone CS-2593 4(5H)-Thiazolone, 2-amino-5-[(4-hydroxyphenyl)methylene]-, (5Z)- (Z)-2-Amino-5-(4-hydroxybenzylidene)thiazol-4(5H)-one (Z)-Mirin (Z)-Mirin,Inhibitor,(Z)Mirin,(Z) Mirin,inhibit (5Z) -2-amino-5- [(4-hydroxyphenyl) methylene] -4 (5H) - thiazolidone 1198097-97-0