EC 1.1.1.42
- CAS No.
- 9028-48-2
- Chemical Name:
- EC 1.1.1.42
- Synonyms
- IDH;ICDH;IDH1;MGC55806;MGC171441;MGC174090;EC 1.1.1.42;EC 1.1.1.42 TYPE I;EC 1.1.1.42 TYPE IV;:THREO-DS-ISOCITRATE
- CBNumber:
- CB8395171
- Molecular Formula:
- NULL
- Molecular Weight:
- 0
- MDL Number:
- MFCD00131420
- MOL File:
- Mol file
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H315-H319-H335 |
Precautionary statements | P280-P302+P352-P362+P364 |
WGK Germany | 3 |
F | 10 |
HS Code | 3507909090 |
EC 1.1.1.42 price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | I5036 | Isocitrate Dehydrogenase 1 (NADP+) human recombinant, expressed in E. coli, lyophilized powder, ≥80?units/mg protein | 9028-48-2 | 100μg | $517 | 2024-03-01 | Buy |
Sigma-Aldrich | I2411 | Isocitrate Dehydrogenase 1 (NADP+) human recombinant, expressed in Sf9 cells, ≥90% (SDS-PAGE) | 9028-48-2 | 10μg | $717 | 2024-03-01 | Buy |
Sigma-Aldrich | I1877 | Isocitric Dehydrogenase (NADP) from porcine heart Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart) | 9028-48-2 | 500mg | $130.8 | 2024-03-01 | Buy |
Sigma-Aldrich | I1877 | Isocitric Dehydrogenase (NADP) from porcine heart Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart) | 9028-48-2 | 1g | $393 | 2024-03-01 | Buy |
Sigma-Aldrich | I2002 | Isocitric Dehydrogenase (NADP) from porcine heart Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein | 9028-48-2 | 25mg | $112 | 2024-03-01 | Buy |
EC 1.1.1.42 Chemical Properties,Uses,Production
Uses
Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .
General Description
Isocitrate dehydrogenase 1 (IDH1) gene is located on human chromosome 2q33. IDH1 is present in the cytoplasm and peroxisomes. It is expressed at high levels in the mammalian liver. IDH1 consists of a C-terminal tripeptide peroxisome, that targets the signal one sequence.
Biochem/physiol Actions
Isocitrate dehydrogenase 1 (IDH1) help in the oxidative carboxylation of isocitrate to α-ketoglutarate, that results in the formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH). It participates in lipid metabolism and glucose sensing. Suppressing IDH1 in pancreatic islets affects the insulin secretion, induced by glucose and leads to increase in lactate production.
EC 1.1.1.42 Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
Wuhan Fortuna Chemical Co.,Ltd | +8618007136271 | hk@fortunachem.com | China | 5984 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
Adamas Reagent, Ltd. | 400-6009262 16621234537 | chenyj@titansci.com | China | 14104 | 59 |
Shanghai BeiZhuo Biotech Co., Ltd. | 021-61119791,13386096464 | bzswkf@foxmail.com | China | 3924 | 50 |
Shanghai JONLN Reagent Co., Ltd. | 400-0066400 13621662912 | 422131432@qq.com | China | 9986 | 55 |
View Lastest Price from EC 1.1.1.42 manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2019-07-06 | EC 1.1.1.42
9028-48-2
|
US $1.00 / kg | 1kg | 95%-99% | 1000kg | Career Henan Chemical Co |
- EC 1.1.1.42
9028-48-2
- US $1.00 / kg
- 95%-99%
- Career Henan Chemical Co
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